Recent advances in the mechanisms and treatment of immune thrombocytopenia

D Provan, JW Semple - EBioMedicine, 2022 - thelancet.com
Primary immune thrombocytopenia is an autoimmune disease associated with a reduced
peripheral blood platelet count. The phenotype is variable with some patients suffering no …

Targeting dendritic cells to advance cross-presentation and vaccination outcomes

C Macri, D Jenika, C Ouslinis, JD Mintern - Seminars in immunology, 2023 - Elsevier
Dendritic cells (DCs) are a complex network of specialised antigen-presenting cells that are
critical initiators of adaptive immunity. Targeting antigen directly to DCs in situ is a …

The role of dendritic cells and their immunometabolism in rheumatoid arthritis

Y Suwa, Y Nagafuchi, S Yamada, K Fujio - Frontiers in Immunology, 2023 - frontiersin.org
Dendritic cells (DCs) play crucial roles in the pathogenesis of rheumatoid arthritis (RA), a
prototypic autoimmune disease characterized by chronic synovitis and joint destruction …

Dendritic cell vaccines improve the glioma microenvironment: Influence, challenges, and future directions

J Zhou, L Li, M Jia, Q Liao, G Peng, G Luo… - Cancer …, 2023 - Wiley Online Library
Introduction Gliomas, especially the glioblastomas, are one of the most aggressive
intracranial tumors with poor prognosis. This might be explained by the heterogeneity of …

Guidelines for mouse and human DC generation

MB Lutz, S Ali, C Audiger, SE Autenrieth… - European journal of …, 2023 - Wiley Online Library
This article is part of the Dendritic Cell Guidelines article series, which provides a collection
of state‐of‐the‐art protocols for the preparation, phenotype analysis by flow cytometry …

[HTML][HTML] Bacteria-mediated metformin-loaded peptide hydrogel reprograms the tumor immune microenvironment in glioblastoma

L Zhu, J Liu, M Qiu, J Chen, Q Liang, G Peng, Z Zou - Biomaterials, 2022 - Elsevier
The tumor immune microenvironment (TIME) is one of the significant hallmarks of cancer
and has the important role of largely determining the malignancy level of tumors. As an …

Crosstalk between dendritic cells and regulatory T cells: Protective effect and therapeutic potential in multiple sclerosis

R Li, H Li, X Yang, H Hu, P Liu, H Liu - Frontiers in Immunology, 2022 - frontiersin.org
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
related to autoimmunity and is characterized by demyelination, neuroinflammation, and …

Naringenin as a natural immunomodulator against T cell-mediated autoimmune diseases: literature review and network-based pharmacology study

Z Liu, X Niu, J Wang - Critical reviews in food science and nutrition, 2023 - Taylor & Francis
Abstract T cells, especially CD4+ T helper (Th) cells, play a vital role in the pathogenesis of
specific autoimmune diseases. Naringenin, a citrus flavonoid, exhibits anti-inflammatory, anti …

The vicious cycle of chronic endometriosis and depression—an immunological and physiological perspective

S Sherwani, MWA Khan, S Rajendrasozhan… - Frontiers in …, 2024 - frontiersin.org
Endometriosis is a chronic, estrogen-dependent, proinflammatory disease that can cause
various dysfunctions. The main clinical manifestations of endometriosis include chronic …

[HTML][HTML] A pseudotyped adenovirus serotype 5 vector with serotype 49 fiber knob is an effective vector for vaccine and gene therapy applications

CM Bliss, SL Hulin-Curtis, M Williams… - … Therapy Methods & …, 2024 - cell.com
Adenoviruses (Ads) have demonstrated significant success as replication-deficient (RD)
viral vectored vaccines, as well as broad potential across gene therapy and cancer therapy …