Challenges to Laboratory Monitoring of Direct Oral Anticoagulants

J Qiao, MH Tran - Clinical and Applied Thrombosis …, 2024 - journals.sagepub.com
Direct oral anticoagulants (DOACs) exert anticoagulation effect by directly inhibiting Factor
Xa (rivaroxaban, apixaban, and edoxaban) or thrombin (dabigatran). Though DOACs are …

[HTML][HTML] Association Between Direct Oral Anticoagulant Concentrations and Clinical Outcomes: A Systematic Review and Meta-Analysis

B Stretton, P Harford, J Kovoor, S Bacchi… - Surgery in Practice and …, 2023 - Elsevier
Introduction Current guidelines suggest preoperative direct oral anticoagulant levels of< 30-
50ng/ml. However, there is limited evidence to guide this expert consensus. Reviewing …

Quantifying time from last dose: do direct oral anticoagulant assays correlate with patient's reported last dose

B Stretton, J Kovoor, S Bacchi, A Gupta… - Blood Coagulation & …, 2023 - journals.lww.com
Results Patient-recalled last dose and DOAC assay was available in 285 individuals. DOAC
assay titres correlated strongly with the expected levels based on a patient's reported last …