The analogs of nitrogen-based heterocycles occupy an exclusive position as a valuable
source of therapeutic agents in medicinal chemistry. More than 75% of drugs approved by …

The molecular hybridization approach has been used to develop compounds with improved
efficacy by combining two or more pharmacophores of bioactive scaffolds. In this context …

The continuous demand of medicinally important scaffolds has prompted the synthetic
chemists to identify simple and efficient routes for their synthesis. 1H-1, 2, 3-triazole …

Bacterial resistance remains a significant threat and a leading cause of death worldwide,
despite massive attempts to control infections. In an effort to develop biologically active …

Tuberculosis, a disease of poverty is a communicable infection with a reasonably high
mortality rate worldwide. 10 Million new cases of TB were reported with approx 1.4 million …

A new series of triazole-thiazole hybrids were designed, synthesized by the Multi-
component reaction approach and evaluated in vitro antimicrobial activity. Most of the tested …

Molecular hybridization is one of the recent strategies to synthesize a novel hybrid
compound by combining two or more pharmacophoric units. Being a linkage process, it …

Celastrol, a quinone‐methide triterpenoid, was extracted from Tripterygium wilfordii Hook. F.
in 1936 for the first time. Almost 70 years later, it is considered one of the molecules most …

Molecular hybridization is one of the recent stratagems in medicinal chemistry to synthesize
a novel hybrid molecule having better affinity and efficacy by combining two or more …

Carbon steel is widely used in the petroleum industry for pipelines, storage tanks, and
equipment due to its mechanical properties, and strength. However, challenges such as …