Surmounting cancer drug resistance: New insights from the perspective of N6-methyladenosine RNA modification

B Li, J Jiang, YG Assaraf, H Xiao, ZS Chen… - Drug resistance …, 2020 - Elsevier
Despite the development of targeted therapy, drug resistance remains a primary hindrance
to curative treatment of various cancers. Among several novel approaches to overcome drug …

Targeting RNA N6-methyladenosine to synergize with immune checkpoint therapy

X Zhou, C Li, T Chen, W Li, X Wang, Q Yang - Molecular Cancer, 2023 - Springer
Cancer immunotherapy, especially immune checkpoint therapy, has revolutionized
therapeutic options by reactivating the host immune system. However, the efficacy varies …

The m6A RNA demethylase ALKBH5 promotes radioresistance and invasion capability of glioma stem cells

A Kowalski-Chauvel, MG Lacore, F Arnauduc… - Cancers, 2020 - mdpi.com
Simple Summary Glioblastoma stem cells (GBMSCs), which are particularly radio-resistant
and invasive, are responsible for the high recurrence of glioblastoma (GBM). Therefore …

Repositioning of anti-inflammatory drugs for the treatment of cervical cancer sub-types

M Kori, KY Arga, A Mardinoglu, B Turanli - Frontiers in Pharmacology, 2022 - frontiersin.org
Cervical cancer is the fourth most commonly diagnosed cancer worldwide and, in almost all
cases is caused by infection with highly oncogenic Human Papillomaviruses (HPVs). On the …

The Interaction of Human Papillomavirus Infection and Prostaglandin E2 Signaling in Carcinogenesis: A Focus on Cervical Cancer Therapeutics

J García-Quiroz, B Vázquez-Almazán… - Cells, 2022 - mdpi.com
Chronic infection by high-risk human papillomaviruses (HPV) and chronic inflammation are
factors associated with the onset and progression of several neoplasias, including cervical …

Fenamates: Forgotten treasure for cancer treatment and prevention: Mechanisms of action, structural modification, and bright future

J Li, X Wang, H Zhang, X Hu, X Peng… - Medicinal Research …, 2025 - Wiley Online Library
Fenamates as classical nonsteroidal anti‐inflammatory agents are widely used for relieving
pain. Preclinical studies and epidemiological data highlight their chemo‐preventive and …

Proteomics analysis of meclofenamic acid‐treated small cell lung carcinoma cells revealed changes in cellular energy metabolism for cancer cell survival

S Yanar, M Kasap, A Kanli, G Akpinar… - … of Biochemical and …, 2023 - Wiley Online Library
Small cell lung carcinoma (SCLC) is a highly aggressive cancer with low survival rate.
Although initial response to chemotherapy in SCLC patients is well‐rated, the treatments …

Advances in molecular mechanism of HPV16 E5 oncoprotein carcinogenesis

B Chen, L Zhao, R Yang, T Xu - Archives of Biochemistry and Biophysics, 2023 - Elsevier
For a considerable duration, cervical cancer has posed a significant risk to the well-being
and survival of women. The emergence and progression of cervical cancer have garnered …

Niosomal formulation of mefenamic acid for enhanced cancer targeting; preparation, characterization and biodistribution study using radiolabeling technique

MA Shewaiter, AA Selim, HM Rashed… - Journal of Cancer …, 2023 - Springer
Background This work aimed to prepare niosomal formulations of an anticancer agent
[mefenamic acid (MEF)] to enhance its cancer targeting. 131I was utilized as a radiolabeling …

Two isostructural Co (II) flufenamato and niflumato complexes with bathocuproine: Analogues with a different cytotoxic activity

L Smolko, R Smolková, E Samoľová, I Morgan… - Journal of Inorganic …, 2020 - Elsevier
Two novel Co (II) fenamato complexes containing bathocuproine (bcp), namely [Co
(bcp)(flu) 2](1) and [Co (bcp)(nif) 2](2)(flu= flufenamato, nif= niflumato) were synthesized and …