Mechanisms of neuroplasticity and brain degeneration: strategies for protection during the aging process

M Toricelli, AAR Pereira, GS Abrao… - Neural regeneration …, 2021 - journals.lww.com
Aging is a dynamic and progressive process that begins at conception and continues until
death. This process leads to a decrease in homeostasis and morphological, biochemical …

The molecular effects of environmental enrichment on Alzheimer's disease

AKY Liew, CH Teo, T Soga - Molecular neurobiology, 2022 - Springer
Environmental enrichment (EE) is an environmental paradigm encompassing sensory,
cognitive, and physical stimulation at a heightened level. Previous studies have reported the …

Enriched environment-induced neuroplasticity in ischemic stroke and its underlying mechanisms

PP Han, Y Han, XY Shen, ZK Gao, X Bi - Frontiers in cellular …, 2023 - frontiersin.org
Stroke is a common cerebrovascular disease that can interrupt local blood flow in the brain,
causing neuronal damage or even death, resulting in varying degrees of neurological …

[HTML][HTML] Cognitive training using fully immersive, enriched environment virtual reality for patients with mild cognitive impairment and mild dementia: Feasibility and …

SJ Yun, MG Kang, D Yang, Y Choi, H Kim… - JMIR Serious …, 2020 - games.jmir.org
Background: Cognitive training using virtual reality (VR) may result in motivational and
playful training for patients with mild cognitive impairment and mild dementia. Fully …

Environmental enrichment improves cognitive function, learning, memory and anxiety-related behaviours in rodent models of dementia: implications for future study

SNM Sahini, NAMN Hazalin, BN Srikumar… - … of Learning and …, 2024 - Elsevier
Environmental enrichment (EE) is a process of brain stimulation by modifying the
surroundings, for example, by changing the sensory, social, or physical conditions. Rodents …

[HTML][HTML] Enriched environment remedies cognitive dysfunctions and synaptic plasticity through NMDAR-Ca2+-Activin A circuit in chronic cerebral hypoperfusion rats

X Zhang, X Shi, J Wang, Z Xu, J He - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Chronic cerebral ischemia (CCI) is one of the critical factors in the occurrence and
development of vascular cognitive impairment (VCI). Apoptosis of nerve cells and changes …

Environmental eustress modulates β-ARs/CCL2 axis to induce anti-tumor immunity and sensitize immunotherapy against liver cancer in mice

C Liu, Y Yang, C Chen, L Li, J Li, X Wang… - Nature …, 2021 - nature.com
Although psycho-social stress is a well-known factor that contributes to the development of
cancer, it remains largely unclear whether and how environmental eustress influences …

How do modifiable risk factors affect Alzheimer's disease pathology or mitigate its effect on clinical symptom expression?

V Ourry, AP Binette, F St-Onge, C Strikwerda-Brown… - Biological …, 2024 - Elsevier
Epidemiological studies show that modifiable risk factors account for approximately 40% of
the population variability in risk of developing dementia, including sporadic Alzheimer's …

Treating Alzheimer's disease with brain stimulation: From preclinical models to non-invasive stimulation in humans

I Lanni, G Chiacchierini, C Papagno… - Neuroscience & …, 2024 - Elsevier
Alzheimer's disease (AD) is a severe and progressive neurodegenerative condition that
exerts detrimental effects on brain function. As of now, there is no effective treatment for AD …

[HTML][HTML] Non-invasive sensory neuromodulation in epilepsy: Updates and future perspectives

Z Li, L Chen, C Xu, Z Chen, Y Wang - Neurobiology of Disease, 2023 - Elsevier
Epilepsy, one of the most common neurological disorders, often is not well controlled by
current pharmacological and surgical treatments. Sensory neuromodulation, including multi …