Background Mounting evidence indicates that obesity may be associated with the risk of
colorectal cancer (CRC). To conduct a systematic review of prospective studies assessing …

Results from cohort studies of adult weight gain and risk of colorectal cancer are
inconsistent. We conducted a systematic review and meta-analysis of prospective studies …

Background High body-mass index (BMI) predisposes to several site-specific cancers, but a
large-scale systematic and detailed characterisation of patterns of risk across all common …

Purpose There is no published dose–response meta-analysis on the association between
height and colorectal cancer risk (CRC) by sex and anatomical sub-site. We conducted a …

The mechanistic target of rapamycin (mTOR) integrates growth factor signals with cellular
nutrient and energy levels and coordinates cell growth, proliferation and survival. A …

Epidemiological evidence continues to accumulate on the benefits of physical activity in
relation to cancer risk, progression and mortality. Recent studies suggest that sedentary …

Background Observational studies examining associations between adult height and risk of
colorectal, prostate, and lung cancers have generated mixed results. We conducted meta …

While there is convincing evidence that excess body fatness in adulthood is positively
associated with colorectal cancer risk, the association between body fatness at an early age …

Objective This meta-analysis examines the relationship between early-life obesity and risk of
colorectal cancer (CRC) in adulthood. Methods A systematic search of Google Scholar …

We investigated occupational energy expenditure and sitting time in the longest held job (in
men only), nonoccupational physical activity, and former sports participation in relation to …