Osteochondral defects (ie, defects which affect both the articular cartilage and underlying
subchondral bone) are often associated with mechanical instability of the joint, and therefore …

Cartilage is considered to be a simple tissue that should be easy to engineer because it is
avascular and contains just one cell type, the chondrocyte. Despite this apparent simplicity …

Meniscus injuries are prevalent in orthopedic diagnosis. The reconstruction of the structural
inhomogeneity and anisotropy of the meniscus is a major challenge in clinical practice …

Background Stem-cell-based, tissue engineered transplants might offer new therapeutic
options for patients, including children, with failing organs. The reported replacement of an …

Background Autologous native cartilage from the nasal septum, ear, or rib is the standard
material for surgical reconstruction of the nasal alar lobule after two-layer excision of non …

In vivo niche plays an important role in determining the fate of exogenously implanted stem
cells. Due to the lack of a proper chondrogenic niche, stable ectopic chondrogenesis of …

The creation of scaffolds for cartilage tissue engineering has faced significant challenges in
developing constructs that can provide sufficient biomechanical support and offer suitable …

Objective To identify markers associated with the chondrogenic capacity of expanded
human articular chondrocytes and to use these markers for sorting of more highly …

This study investigated the use of a type II collagen-glycosaminoglycan (CG) scaffold as a
nonviral gene delivery vehicle for facilitating gene transfer to seeded adult articular …

Efficient, reproducible, and precise methodologies for fabricating tissue engineering (TE)
scaffolds using three-dimensional (3D) printing techniques are evaluated. Fusion deposition …