Ethnopharmacological relevance Network pharmacology is a new discipline based on
systems biology theory, biological system network analysis, and multi-target drug molecule …

Traditional Chinese medicine (TCM) has a long history of viewing an individual or patient as
a system with different statuses, and has accumulated numerous herbal formulae. The …

A central goal of systems biology is to elucidate the structural and functional architecture of
the cell. To this end, large and complex networks of molecular interactions are being rapidly …

中医药具有以整体观和辨证论治为特色的理论体系和几千年的临床实践经验,
中医药现代化亟需建立符合其整体特点的科学研究方法. 随着医学与生命科学研究步入大数据 …

The one-drug/one-target/one-disease approach to drug discovery is presently facing many
challenges of safety, efficacy, and sustainability. Network biology and polypharmacology …

The concept of “network target” has ushered in a new era in the field of traditional Chinese
medicine (TCM). As a new research approach, network pharmacology is based on the …

Abstract Traditional Chinese Medicine (TCM), a crucial component of the current medical
system, has been extensively used in clinical practice due to its valuable therapeutic …

Multi-target and combinatorial therapies have been focused for the past several decades.
These approaches achieved considerable therapeutic efficacy by modulating the activities of …

Ban‐Xia‐Xie‐Xin‐Tang (BXXXT) is a classical formula from Shang‐Han‐Lun which is one of
the earliest books of TCM clinical practice. In this work, we investigated the therapeutic …

Motivation Many approaches in systems biology have been applied in drug repositioning
due to the increased availability of the omics data and computational biology tools. Using a …