Splenectomy for immune thrombocytopenia: down but not out

S Chaturvedi, DM Arnold… - Blood, The Journal of the …, 2018 - ashpublications.org
Splenectomy is an effective therapy for steroid-refractory or dependent immune
thrombocytopenia (ITP). With the advent of medical alternatives such as rituximab and …

Splenectomy for adult patients with idiopathic thrombocytopenic purpura: a systematic review to assess long-term platelet count responses, prediction of response …

K Kojouri, SK Vesely, DR Terrell, JN George - Blood, 2004 - ashpublications.org
Splenectomy has been a standard treatment for adult patients with idiopathic
thrombocytopenic purpura (ITP) for more than 50 years. However, the durability of …

[HTML][HTML] Benefits and risks of splenectomy

EP Weledji - International Journal of Surgery, 2014 - Elsevier
Splenectomy is a powerful therapeutic procedure in a wide variety of medical disorders
provided that it is not undertaken lightly and the risks are weighed against the potential …

How I treat idiopathic thrombocytopenic purpura (ITP)

DB Cines, JB Bussel - Blood, 2005 - ashpublications.org
Our goal is to set forth our opinion of the best approach to managing adults with primary
idiopathic (autoimmune) thrombocytopenic purpura (ITP), with emphasis on the word …

Rituximab efficacy and safety in adult splenectomy candidates with chronic immune thrombocytopenic purpura: results of a prospective multicenter phase 2 study

B Godeau, R Porcher, O Fain, F Lefrère… - Blood, The Journal …, 2008 - ashpublications.org
Whether rituximab could effectively and safely avoid splenectomy for adults with chronic
immune thrombocytopenic purpura (ITP) remains unresolved. A multicenter, prospective …

Management of immune thrombocytopenic purpura in adults

R Stasi, D Provan - Mayo Clinic Proceedings, 2004 - Elsevier
Primary immune thrombocytopenic purpura (ITP), also referred to as idiopathic
thrombocytopenic purpura, is an organ-specific autoimmune disorder in which …

Efficacy and safety of splenectomy in immune thrombocytopenic purpura: long-term results of 402 cases

N Vianelli, M Galli, A de Vivo, T Intermesoli… - …, 2005 - haematologica.org
BACKGROUND AND OBJECTIVES: Immune thrombocytopenic purpura (ITP) is an acquired
autoimmune disease characterized by platelet destruction. Glucocorticoids are the first …

Long term follow‐up after splenectomy performed for immune thrombocytopenic purpura (ITP)

J Schwartz, MD Leber, S Gillis, A Giunta… - American journal of …, 2003 - Wiley Online Library
Splenectomy is the only treatment of ITP known to have “curative” effects in a substantial
fraction of patients. However, the true long‐term outcome is uncertain and controversial …

Update on diagnosis and treatment of immune thrombocytopenia

R Sandal, K Mishra, A Jandial, KK Sahu… - Expert review of …, 2021 - Taylor & Francis
Background Immune thrombocytopenia (ITP) is a heterogeneous acquired disorder
characterized by isolated thrombocytopenia whose exact pathogenesis is not yet clear …

Management of adult idiopathic thrombocytopenic purpura

DB Cines, R McMillan - Annu. Rev. Med., 2005 - annualreviews.org
Idiopathic thrombocytopenic purpura (ITP) is a common hematologic disorder manifested by
immune-mediated thrombocytopenia. The diagnosis remains one of exclusion, after other …