Aortic dissections and aortic aneurysms are fatal events characterized by structural changes
to the aortic wall. The maximum diameter criterion, typically used for aneurysm rupture risk …

Cardiovascular diseases are the leading cause of death worldwide and include, among
others, critical conditions of the aortic wall. Importantly, such critical conditions require …

Bicuspid aortic valve disease is the most common congenital cardiac disorder, being
present in 1% to 2% of the general population. Associated aortopathy is a common finding in …

Objectives This study sought to ascertain whether patients with a bicuspid aortic valve (BAV)
have an intrinsic alteration in regional aortic stiffness compared with patients with tricuspid …

Extracellular matrix (ECM)-derived bioscaffolds have been shown to elicit tissue repair
through retention of bioactive signals. Given that the adventitia of large blood vessels is a …

Bicuspid aortic valve (BAV) is the most common congenital valvular defect and is associated
with ascending aortic dilation (AAD) in a quarter of patients. AAD has been ascribed both to …

Objective Patients with a bicuspid aortic valve have increased susceptibility to the
development of ascending aortic dilation and dissection compared with persons with a …

Aneurysms of the ascending thoracic aorta often require prophylactic surgical intervention to
resect and replace the aortic wall with a synthetic graft to avoid the risk of dissection or …

Background The prevalence for thoracic aortic aneurysms (TAAs) is significantly increased
in patients with a bicuspid aortic valve (BAV) compared with patients who have a normal …

Abstract Structure-based constitutive models might help in exploring mechanisms by which
arterial wall histology is linked to wall mechanics. This study aims to validate a recently …