Role of the receptor for advanced glycation end products in the severity of SARS-CoV-2 infection in diabetic patients

A Pedreañez, JA Mosquera-Sulbaran, D Tene - Diabetology International, 2024 - Springer
Abstract Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, is a severe
disease in older adults and in individuals with associated comorbidities such as diabetes …

Altered expression pattern of immune response-related genes and isoforms in hypersensitivity pneumonitis lung fibroblasts

AL Torres-Machorro, C Becerril, E Hernández-Plata… - Scientific Reports, 2024 - nature.com
Hypersensitivity pneumonitis (HP) is an immune-mediated inflammatory interstitial lung
disease that may evolve to pulmonary fibrosis, a progressive disorder with a poor prognosis …

[HTML][HTML] Effect of advanced glycation end-products in a wide range of medical problems including COVID-19

A Bronowicka-Szydełko, K Gostomska-Pampuch… - Advances in Medical …, 2024 - Elsevier
Glycation is a physiological process that determines the aging of the organism, while in
states of metabolic disorders it is significantly intensified. High concentrations of compounds …

Novel inflammatory biomarkers in the prognosis of COVID-19

K Zhan, L Wang, H Lin, X Fang… - … in Respiratory Disease, 2023 - journals.sagepub.com
Background: The central role of inflammatory progression in the development of
Coronavirus disease 2019 (COVID-19), especially in severe cases, is indisputable …

Significance of nitrosative stress and glycoxidation products in the diagnosis of COVID-19

B Wolszczak-Biedrzycka, J Dorf, J Matowicka-Karna… - Scientific Reports, 2024 - nature.com
Nitrosative stress promotes protein glycoxidation, and both processes can occur during an
infection with the SARS-CoV-2 virus. Therefore, the aim of this study was to assess selected …

[HTML][HTML] Persistent Post COVID-19 endothelial dysfunction and oxidative stress in women

N Semenova, E Vyrupaeva, S Kolesnikov… - Pathophysiology, 2024 - mdpi.com
The assessment of endothelial dysfunction and free radical homeostasis parameters were
performed in 92 women, aged 45 to 69 years, divided into the following groups: women …

Clustering based on renal and inflammatory admission parameters in critically ill patients admitted to the ICU

O Mascle, C Dupuis, M Brailova, B Bonnet, A Mirand… - PloS one, 2024 - journals.plos.org
Introduction The COVID-19 pandemic has been associated with significant variability in
acute kidney injury (AKI) incidence, leading to concerns regarding patient heterogeneity …

Redox Biomarkers–An Effective Tool for Diagnosing COVID-19 Patients and Convalescents

B Wolszczak-Biedrzycka, J Dorf… - Journal of …, 2024 - Taylor & Francis
Aim COVID-19 triggers the overproduction of reactive oxygen species (ROS) which, in
combination with a weakened antioxidant barrier, can lead to protein oxidation and lipid …

Anti-Viral and Anti-Inflammatory Therapeutic Effect of RAGE-Ig Protein Against Multiple SARS-CoV-2 Variants of Concern Demonstrated in K18-hACE2 Mouse and …

NR Dhanushkodi, S Prakash, A Quadiri, L Zayou… - J Immunol, 2024 - journals.aai.org
SARS-CoV-2 variants of concern (VOCs) continue to evolve and reemerge with chronic
inflammatory long COVID sequelae, necessitating the development of anti-inflammatory …

Design and synthesis of glycyrrhetinic acid glycosides against acute lung injury and pulmonary fibrosis

W Li, J Liu, T Wu, X Qiang, Y Peng, Q Zhao, D He - Molecular Diversity, 2024 - Springer
HMGB1 mediated signalling pathway plays an important role in acute injury and fibrosis in
lung tissues. Glycyrrhizic acid (GL) is a HMGB1 inhibitor, and its aglycone (glycyrrhetinic …