Tumours display an astonishing variation in the spatial distribution, composition and
activation state of immune cells, which impacts their progression and response to …

Tumors are not only aggregates of malignant cells but also well-organized complex
ecosystems. The immunological components within tumors, termed the tumor immune …

As an efficient class of hydrogel-based therapeutic drug delivery systems, deoxyribonucleic
acid (DNA) hydrogels (particularly DNA nanogels) have attracted massive attention in the …

Immune cell infiltration is an important indicator of whether tumor patients will benefit from
immunotherapy. Gastric cancer is one of the most common tumors in the world, and new …

Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous disease arising
from the mucosa of the upper aerodigestive tract. Despite multimodality treatments …

Importance After 10 pack-years of smoking was initially established as a threshold for risk
stratification, subsequent clinical trials incorporated it to identify candidates for treatment …

Importance Given the role of inflammation in cancer progression, neutrophil-lymphocyte
ratio (NLR) from peripheral blood has been suggested as a readout of systemic …

There are few prognostic biomarkers and targeted therapeutics currently in use for the
clinical management of oral squamous cell carcinoma (OSCC) and patient outcomes remain …

Simple Summary During the last decades, scientific advances in immuno-oncology and a
better understanding of tumors' immune profile led to the development of novel …

Objective To evaluate the relation between PD‐L1 expression in oral cavity squamous cell
carcinomas and clinicopathological features as well as survival outcomes. Methods A …