Anticancer treatment using cytotoxic drugs is considered to mediate cell death by activating
key elements of the apoptosis program and the cellular stress response. While proteolytic …

Sunburn cells, single standing cells with typical morphologic features occurring in UV‐
exposed skin, have been recognized as keratinocytes undergoing apoptosis following UV …

The skin typically tolerates exposure to various microbes and chemicals in the environment.
Here, we investigated how the epidermis maintains this innate immune tolerance to stimuli …

Immune therapy of cancer is among the most promising recent advances in medicine.
Whether the immune system can keep cancer in check depends on, among other factors, the …

The cellular responses to various form of radiation, including ionizing-and UV-irradiation or
exposure to electromagnetic fields is manifested as irreversible and reversible structural and …

Hydroxynonenal (HNE), a diffusible product of lipid peroxidation, has been suggested to be
a key mediator of oxidative stress-induced cell death. In this study, we partially characterized …

Apoptosis induced by cadmium has been shown in many tissues in vivo and in cultured cells
in vitro. However, its molecular mechanism is not fully understood. When the human …

Apoptosis in response to cellular stress such as treatment with cytotoxic drugs is mediated
by effector caspases (caspase-3) which can be activated by different initiator pathways …

The nuclear self-Ags targeted in systemic lupus erythematosus translocate to the cell
membrane of UV-irradiated apoptotic keratinocytes and may represent an important source …

The role of cardiocytes in physiologic removal of apoptotic cells and the subsequent effect of
surface binding by anti-SSA/Ro and-SSB/La antibodies was addressed. Initial experiments …