Langerhans cell histiocytosis (LCH) is an inflammatory neoplasia of myeloid precursor cells
driven by mutations in the mitogen-activated protein kinase pathway. When disease involves …

Langerhans cell histiocytosis is a rare group of disorders without a well-understood etiology.
Known formerly as histiocytosis X, the disease has a wide spectrum of clinical presentations …

Abstract Background/Objectives Langerhans cell histiocytosis (LCH), a rare neoplasm of
hematopoietic myeloid precursor cells, is clinically characterized by spontaneously resolving …

This comprehensive review of the histopathology of the human nail will act as a masterclass
for all dermatologists, dermatopathologists, and nail-interested pathologists who have to …

Rare diseases affect less than 1 in 2000 people and are characterized by a serious, chronic,
and progressive course. Among the described diseases, a mutation in a single gene caused …

The clinical differential diagnosis of many tumors in the nail area is difficult. The nail plate
both covers the lesions and may influence the pattern of invasion. Most benign tumors cause …

Objective To report a single centre outcome of management of Langerhans cell histiocytosis
(LCH), a clonal disease with involvement of various body systems. Methods Retrospective …

Langerhans cell histiocytosis (LCH) and adult-onset xanthogranuloma (AXG) are rare
disorders characterized by the accumulation of macrophage, dendritic cells, or monocyte …

This article presents a case study of an 8-week-old male infant with nail changes. The infant
developed thickening of a few fingernails at 3 weeks of age, which later spread to all …

Objective To ascertain the growth and endocrinal disturbances associated with Pediatric
Langerhans Cell Histiocytosis (LCH). Methods Retrospective analysis of hospital records of …