Immune modulation by mesenchymal stem cells

W Jiang, J Xu - Cell proliferation, 2020 - Wiley Online Library
Mesenchymal stem cells (MSCs) can be derived from various adult tissues with multipotent
and self‐renewal abilities. The characteristics of presenting no major ethical concerns …

Immunomodulatory and regenerative effects of mesenchymal stem cells and extracellular vesicles: therapeutic outlook for inflammatory and degenerative diseases

S Dabrowska, A Andrzejewska, M Janowski… - Frontiers in …, 2021 - frontiersin.org
Mesenchymal stem cells (MSCs) are non-hematopoietic, multipotent stem cells derived from
mesoderm, which can be easily isolated from many sources such as bone marrow, umbilical …

Interactions between mesenchymal stem cells and the immune system

N Li, J Hua - Cellular and Molecular Life Sciences, 2017 - Springer
In addition to being multi-potent, mesenchymal stem cells (MSCs) possess
immunomodulatory functions that have been investigated as potential treatments in various …

Stem cell therapy in heart diseases–cell types, mechanisms and improvement strategies

P Müller, H Lemcke, R David - Cellular Physiology and Biochemistry, 2018 - karger.com
A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …

[HTML][HTML] Mesenchymal stromal cells and the innate immune response

K Le Blanc, LC Davies - Immunology letters, 2015 - Elsevier
Mesenchymal stromal cells (MSC) have been exploited for their immunomodulatory
properties in the treatment of a number of immune-based disorders, including Graft versus …

Identifying the therapeutic significance of mesenchymal stem cells

VK Mishra, HH Shih, F Parveen, D Lenzen, E Ito… - Cells, 2020 - mdpi.com
The pleiotropic behavior of mesenchymal stem cells (MSCs) has gained global attention due
to their immense potential for immunosuppression and their therapeutic role in immune …

Current strategies to enhance adipose stem cell function: an update

Y Seo, TH Shin, HS Kim - International journal of molecular sciences, 2019 - mdpi.com
Mesenchymal stem cells (MSCs) emerged as a promising therapeutic tool targeting a variety
of inflammatory disorders due to their multiple remarkable properties, such as superior …

The immunomodulatory function of mesenchymal stem cells: mode of action and pathways

A Uccelli, NK de Rosbo - Annals of the New York Academy of …, 2015 - Wiley Online Library
Mesenchymal stem cells (MSCs) are being increasingly investigated as a therapeutic
alternative, not only for their possible regenerative potential but also for their …

The clinical trials of mesenchymal stem cell therapy in skin diseases: an update and concise review

A Golchin, TZ Farahany, A Khojasteh… - Current stem cell …, 2019 - ingentaconnect.com
The skin is one of the crucial body organs with anatomy and physiology linked to various
disorders including congenital and acquired diseases. Nowadays, mesenchymal stem cell …

Stem cell‐derived extracellular vesicles as immunomodulatory therapeutics

Y Seo, HS Kim, IS Hong - Stem cells international, 2019 - Wiley Online Library
Mesenchymal stem cells (MSCs) have been reported to possess regulatory functions on
immune cells which make them alternative therapeutics for the treatment of inflammatory …