Phage-antibiotic cocktail rescues daptomycin and phage susceptibility against daptomycin-nonsusceptible Enterococcus faecium in a simulated endocardial …
AJ Kunz Coyne, K Stamper, A El Ghali… - Microbiology …, 2023 - Am Soc Microbiol
Enterococcus faecium is a difficult-to-treat pathogen with emerging resistance to most
clinically available antibiotics. Daptomycin (DAP) is the standard of care, but even high DAP …
clinically available antibiotics. Daptomycin (DAP) is the standard of care, but even high DAP …
Exploiting phage-antibiotic synergies to disrupt Pseudomonas aeruginosa PAO1 biofilms in the context of orthopedic infections
S De Soir, H Parée, NHN Kamarudin… - Microbiology …, 2024 - Am Soc Microbiol
In recent years, bacteriophages (or phages) have reentered the spotlight as alternative or
adjuvant therapeutic agents to antibiotics. Their efficacy in more recalcitrant forms of …
adjuvant therapeutic agents to antibiotics. Their efficacy in more recalcitrant forms of …
Synergistic bactericidal effects of phage-enhanced antibiotic therapy against MRSA biofilms
AJ Kunz Coyne, K Stamper, C Bleick… - Microbiology …, 2024 - Am Soc Microbiol
Methicillin-resistant Staphylococcus aureus (MRSA) causes biofilm-related medical device
infections. Phage-antibiotic combinations offer potential therapy due to proven in vitro …
infections. Phage-antibiotic combinations offer potential therapy due to proven in vitro …
The virtue of training: extending phage host spectra against vancomycin-resistant Enterococcus faecium strains using the Appelmans method
J Lossouarn, E Beurrier, A Bouteau… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
Phage therapy has (re) emerged as a serious possibility for combating multidrug-resistant
bacterial infections, including those caused by vancomycin-resistant Enterococcus faecium …
bacterial infections, including those caused by vancomycin-resistant Enterococcus faecium …
Bacteriophage and antibiotic combination therapy for recurrent Enterococcus faecium bacteremia
ME Stellfox, C Fernandes, RK Shields, G Haidar… - Mbio, 2024 - Am Soc Microbiol
Enterococcus faecium is a member of the human gastrointestinal (GI) microbiota but can
also cause invasive infections, especially in immunocompromised hosts. Enterococci …
also cause invasive infections, especially in immunocompromised hosts. Enterococci …
Phage-antibiotic synergy against daptomycin-nonsusceptible MRSA in an ex vivo simulated endocardial pharmacokinetic/pharmacodynamic model
AJ Kunz Coyne, C Bleick, K Stamper… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
Phage-antibiotic combinations (PAC) offer a potential solution for treating refractory
daptomycin-nonsusceptible (DNS) methicillin-resistant Staphylococcus aureus (MRSA) …
daptomycin-nonsusceptible (DNS) methicillin-resistant Staphylococcus aureus (MRSA) …