Many genes and molecules that drive tissue patterning during organogenesis and tissue
regeneration have been discovered. Yet, we still lack a full understanding of how these …

Endocytosis allows cells to transport particles and molecules across the plasma membrane.
In addition, it is involved in the termination of signalling through receptor downmodulation …

Evolutionary developmental biology, or Evo-Devo for short, has become an established field
that, broadly speaking, seeks to understand how changes in development drive major …

The dynamic reshaping of tissues during morphogenesis results from a combination of
individual cell behaviors and collective cell rearrangements. However, a comprehensive …

Drosophila germ-band extension (GBE) is an example of the convergence and extension
movements that elongate and narrow embryonic tissues. To understand the collective cell …

How genetic programs generate cell-intrinsic forces to shape embryos is actively studied,
but less so how tissue-scale physical forces impact morphogenesis. Here we address the …

Apical constriction is a major mechanism underlying tissue internalization during
development. This cell constriction typically requires actomyosin contractility. Thus …

The adult form of a multicellular organism is shaped by a series of morphogenetic processes
that organise the body into tissues and organs. Most of these events involve the deformation …

Tight junctions contribute to epithelial barrier function by selectively regulating the quantity
and type of molecules that cross the paracellular barrier. Experimental approaches to …

Tissue morphogenesis is the process in which coordinated movements and shape changes
of large numbers of cells form tissues, organs, and the internal body structure …