The retinal pigment epithelium-photoreceptor interphase is renewed each day in a stunning
display of cellular interdependence. While photoreceptors use photosensitive pigments to …

Background Growing evidence points to a link between specific fatty acids ingested through
the diet and human health. Chain length, saturation degree, and position of double bonds in …

Most irreversible blindness observed with glaucoma and retina-related ocular diseases,
including age-related macular degeneration and diabetic retinopathy, have their origin in the …

Stargardt disease, one of the most common forms of inherited retinal diseases, affects
individuals worldwide. The primary cause is mutations in the ABCA4 gene, leading to the …

The gut microbiota is a complex ecosystem that inhabits the gastrointestinal tract and
consists of archaea, fungi, viruses, and bacteria, with bacteria being dominant. From birth …

Alzheimer disease (AD) is the most prevalent cause of dementia in the elderly. Although
impaired cognition and memory are the most prominent features of AD, abnormalities in …

Autosomal recessive Stargardt disease (STGD1) is an inherited retinal degenerative
disease associated with a mutated ATP-binding cassette, subfamily A, member 4 (ABCA4) …

Age‐related macular degeneration (AMD) is an eye disease, which causes impaired vision
that can lead to blindness. The incidence of AMD increases with age. Retinal pigment …

Cytochrome P450 (CYP) gene mutations are a common predisposition associated with
glaucoma. Although the molecular mechanisms are largely unknown, omega-3 …

Retinitis pigmentosa (RP) is the most common inherited retinal dystrophy causing
progressive vision loss. It is accompanied by chronic and sustained inflammation, including …