Dwellers and trespassers: mononuclear phagocytes at the borders of the central nervous system

DC Ivan, S Walthert, K Berve, J Steudler… - Frontiers in …, 2021 - frontiersin.org
The central nervous system (CNS) parenchyma is enclosed and protected by a multilayered
system of cellular and acellular barriers, functionally separating glia and neurons from …

In vitro models of the choroid plexus and the blood-cerebrospinal fluid barrier: advances, applications, and perspectives

C Schwerk, H Schroten - Human Cell, 2024 - Springer
The choroid plexus (CP), a highly vascularized endothelial–epithelial convolute, is placed in
the ventricular system of the brain and produces a large part of the cerebrospinal fluid (CSF) …

In vitro models of the blood–cerebrospinal fluid barrier and their applications in the development and research of (Neuro) Pharmaceuticals

F Dabbagh, H Schroten, C Schwerk - Pharmaceutics, 2022 - mdpi.com
The pharmaceutical research sector has been facing the challenge of neurotherapeutics
development and its inherited high-risk and high-failure-rate nature for decades. This hurdle …

Breaking the barrier: in vitro models to study choroid plexus development

L Pellegrini, MA Lancaster - Current Opinion in Cell Biology, 2021 - Elsevier
The choroid plexus is central to normal brain function by secreting cerebrospinal fluid and
dynamically regulating its composition throughout development and homoeostasis. Much of …

Collagen-based biomaterials in organoid technology for reproductive medicine: Composition, characteristics, and applications

B Feng, H Yang, M Zhu, J Li, HM Chang… - Collagen and …, 2023 - Springer
Collagen-based biomaterials (CBB) are highly esteemed by researchers in materials
science and biomedicine due to their extensive applications across various biomedical …

Keeping the Cortex Afloat: Cerebrospinal Fluid Contributions to Cerebral Cortical Development

TE Lacey, RM Fame… - … in Development and …, 2023 - Wiley Online Library
Recent work has illuminated mechanisms by which cerebrospinal fluid (CSF) participates in
cerebral cortical development. While providing a protective fluid cushion and sink for waste …

Interleukin-6 at the Crossroads Between Choroid Plexus Clearance Deficits and Cognitive Dysfunction in Neuropsychiatric Lupus

JA Reynolds - 2024 - search.proquest.com
The multi-system, autoimmune disease systemic lupus erythematosus (SLE) often involves
the nervous system. Through largely unexplored mechanisms, patients develop cognitive …

Dwellers and Trespassers: Mononuclear Phagocytes at the Borders of the Central Nervous System

B Stankoff, U Gomez-Pinedo, V Zujovic… - … the Roles of Glia …, 2022 - books.google.com
The central nervous system (CNS) parenchyma is enclosed and protected by a multilayered
system of cellular and acellular barriers, functionally separating glia and neurons from …

Blood-CSF barrier clearance of ABC transporter substrates is suppressed by interleukin-6 in lupus choroid plexus organoids

JA Reynolds, L Torz, N Petersen… - Interleukin-6 drives … - search.proquest.com
The choroid plexus (CP) has been recently implicated in the pathogenesis of the
neuropsychiatric manifestations of systemic lupus erythematosus (NPSLE). SLE patients …

Signal transduction during CNS invasion by Listeria monocytogenes and the role of CD44 in the invasion

F Banovic - 2022 - archiv.ub.uni-heidelberg.de
Listeria monocytogenes (Lm) is an opportunistic, facultatively intracellular pathogen that
enters the host via contaminated food, causing listeriosis. Given opportunity, Lm can enter …