Immunopeptidomics is the survey of all peptides displayed on a cell or tissue when bound to
human leukocyte antigen (HLA) molecules using tandem mass spectrometry. When …

Immunoepigenetics is a growing field, as there is mounting evidence on the key role played
by epigenetic mechanisms in the regulation of tumor immune cell recognition and control of …

Abstract Preferentially Expressed Antigen in Melanoma (PRAME), a cancer-testis antigen,
provides an ideal target for immunotherapy in acute myeloid leukemia (AML). We have …

Although anti-programmed death-1 (PD-1) antibody therapy improves the prognosis in
patients with head and neck squamous cell carcinoma (HNSCC), some patients exhibit …

Angioimmunoblastic T-cell lymphoma (AITL) is a kind of aggressive T-cell lymphoma with
significant enrichment of non-malignant tumor microenvironment (TME) cells. However, the …

Sulfated polysaccharides derived from green marine macroalgae are known for their wide
range of therapeutic properties, including the mitigation of inflammatory disorders. A sulfated …

Introduction Diffuse large B-cell lymphoma (DLBCL) is the most common aggressive
lymphoma. Recent advances in immunotherapy such as chimeric antigen receptor T-cell …

The last two decades have brought ground-breaking advances in genetics, culminating in
deep profiling of the human genome and high resolution detection of genetic variants. These …

弥漫大B 细胞淋巴瘤(diffuse large B cell lymphoma, DLBCL) 是非霍奇金淋巴瘤(non-Hodgkin
lymphoma, NHL) 中最常见的类型, 个体间有很强的异质性, 1/3 患者在治疗中出现耐药 …

Multiple types of MHC‐associated antigens can be targeted in lymphoid malignancies.
Tumor‐associated antigens (TAA) are abnormally expressed self‐antigens. TAA‐based …