Abstract Triple Negative Breast Cancer (TNBC) is the most lethal subtype of breast cancer.
Despite the successes of emerging targeted therapies, relapse, recurrence, and therapy …

Breast cancer stem cells (BCSCs) represent a distinct subpopulation of cells with the ability
to self-renewal and differentiate into phenotypically diverse tumor cells. The involvement of …

Breast cancer which is the most common type of diagnosed cancer among women
worldwide possesses metastatic potential, multi‑drug resistance, and high mortality. The NF …

IKBKE, a non-canonical inflammatory kinase, is frequently amplified or activated, and plays
predominantly oncogenic roles in human cancers, especially in breast cancer. However, the …

Purpose Glioblastoma multiforme (GBM) is the most common and aggressive malignant type
of brain tumor. Despite advances in diagnosis and therapy, the prognosis of patients with …

BET inhibitors (BETi) exhibit a strong anti-tumor activity in triple-negative breast cancer
(TNBC). However, BETi resistance has been reported in TNBC. The mechanisms of …

In recent years, zebrafish (ZF) has been increasingly applied as a model in human disease
studies, with a particular focus on cancer. A number of advantages make it an attractive …

The majority of breast cancers are diagnosed as estrogen receptor–positive (ER+) and
respond well to ER-targeted endocrine therapy. Despite the initial treatability of ER+ breast …

Breast cancer represents a great challenge since it is the first cause of death by cancer in
women worldwide. LncRNAs are a newly described class of non-coding RNAs that …

Cancer stem cells (CSCs) are subpopulations of cancer cells within the tumor bulk that have
emerged as an attractive therapeutic target for cancer therapy. Accumulating evidence has …