The surgeon general of the USA defines osteoporosis as “a skeletal disorder characterized
by compromised bone strength, predisposing to an increased risk of fracture.” Measuring …

In this paper, we review analytical and computational models of bone fracture and strength.
Bone fracture is a complex phenomenon due to the composite, inhomogeneous and …

Finite element (FE) analysis has been applied for the past 40 years to simulate the
mechanical behavior of bone. Although several validation studies have been performed on …

While dual energy X-ray absorptiometry (DXA) is considered the gold standard to evaluate
fracture risk in vivo, in the present study, the quantitative computed tomography (QCT) …

Abstract The International Society for Clinical Densitometry (ISCD) has developed new
official positions for the clinical use of quantitative computed tomography (QCT)-based finite …

High-resolution quantitative computed tomography (HRQCT)-based analysis of spinal bone
density and microstructure, finite element analysis (FEA), and DXA were used to investigate …

The estimation of local and structural mechanical properties of bones with micro Finite
Element (microFE) models based on Micro Computed Tomography images depends on the …

Fractures of the distal section of the radius (Colles' fractures) occur earlier in life than other
osteoporotic fractures. Therefore, they can be interpreted as a warning signal for later, more …

Introduction Pathologic vertebral fractures are a major clinical concern in the management of
cancer patients with metastatic spine disease. These fractures are a direct consequence of …

The mechanism of vertebral wedge fractures remains unclear and may relate to typical
variations in the mechanical behavior of the intervertebral disc. To gain insight, we tested 16 …