The good, the bad, and the ugly with alcohol use and abuse on the heart
RK Walker, VM Cousins, NA Umoh… - Alcoholism: Clinical …, 2013 - Wiley Online Library
Since its advent, alcohol has been utilized throughout history socially, for rituals, worship,
and for its therapeutic, antibacterial, and analgesic properties. In moderation, alcohol …
and for its therapeutic, antibacterial, and analgesic properties. In moderation, alcohol …
Alcohol and cardiovascular disease—modulation of vascular cell function
PA Cahill, EM Redmond - Nutrients, 2012 - mdpi.com
Alcohol is a commonly used drug worldwide. Epidemiological studies have identified
alcohol consumption as a factor that may either positively or negatively influence many …
alcohol consumption as a factor that may either positively or negatively influence many …
Cyclic AMP-dependent phosphorylation of neuronal nitric oxide synthase mediates penile erection
Nitric oxide (NO) generated by neuronal NO synthase (nNOS) initiates penile erection, but
has not been thought to participate in the sustained erection required for normal sexual …
has not been thought to participate in the sustained erection required for normal sexual …
HSP90 modulates T2R bitter taste receptor nitric oxide production and innate immune responses in human airway epithelial cells and macrophages
Bitter taste receptors (T2Rs) are G protein-coupled receptors (GPCRs) expressed in various
cell types including ciliated airway epithelial cells and macrophages. T2Rs in these two …
cell types including ciliated airway epithelial cells and macrophages. T2Rs in these two …
Notch1 mediates preconditioning protection induced by GPER in normotensive and hypertensive female rat hearts
G protein-coupled estrogen receptor (GPER) is an estrogen receptor expressed in the
cardiovascular system. G1, a selective GPER ligand, exerts cardiovascular effects through …
cardiovascular system. G1, a selective GPER ligand, exerts cardiovascular effects through …
Additive renoprotection by pioglitazone and fenofibrate against inflammatory, oxidative and apoptotic manifestations of cisplatin nephrotoxicity: modulation by PPARs
Nephrotoxicity is a major side effect for the antineoplastic drug cisplatin. Here, we employed
pharmacological, biochemical, and molecular studies to investigate the role of peroxisome …
pharmacological, biochemical, and molecular studies to investigate the role of peroxisome …
Role of alcohol oxidative metabolism in its cardiovascular and autonomic effects
MM El-Mas, AA Abdel-Rahman - … to Human Health and Precision Medicine, 2019 - Springer
Several review articles have been published on the neurobehavioral actions of
acetaldehyde and other ethanol metabolites as well as in major alcohol-related disorders …
acetaldehyde and other ethanol metabolites as well as in major alcohol-related disorders …
High-carbohydrate diet enhanced the anticontractile effect of perivascular adipose tissue through activation of renin-angiotensin system
DEF Reis Costa, ALM Silveira, GP Campos… - Frontiers in …, 2021 - frontiersin.org
The perivascular adipose tissue (PVAT) is an active endocrine organ responsible for release
several substances that influence on vascular tone. Increasing evidence suggest that …
several substances that influence on vascular tone. Increasing evidence suggest that …
Role of the macula densa sodium glucose cotransporter type 1-neuronal nitric oxide synthase-tubuloglomerular feedback pathway in diabetic hyperfiltration
An increase of glomerular filtration rate (GFR) is a common observation in early diabetes
and is considered a key risk factor for subsequent kidney injury. However, the mechanisms …
and is considered a key risk factor for subsequent kidney injury. However, the mechanisms …
Effects of Akt Activator SC79 on Human M0 Macrophage Phagocytosis and Cytokine Production
Akt is an important kinase in metabolism. Akt also phosphorylates and activates endothelial
and neuronal nitric oxide (NO) synthases (eNOS and nNOS, respectively) expressed in M0 …
and neuronal nitric oxide (NO) synthases (eNOS and nNOS, respectively) expressed in M0 …