Immunoregulation by resveratrol; implications for normal tissue protection and tumour suppression

AR Lalani, F Fakhari, S Radgoudarzi… - Clinical and …, 2023 - Wiley Online Library
Immune reactions are involved in both tumour and normal tissue in response to therapy.
Elevated secretion of certain chemokines, exosomes and cytokines triggers inflammation …

Tissue fibrosis induced by radiotherapy: current understanding of the molecular mechanisms, diagnosis and therapeutic advances

Z Yu, C Xu, B Song, S Zhang, C Chen, C Li… - Journal of Translational …, 2023 - Springer
Cancer remains the leading cause of death around the world. In cancer treatment, over 50%
of cancer patients receive radiotherapy alone or in multimodal combinations with other …

Metformin intervention—a panacea for cancer treatment?

A Buczyńska, I Sidorkiewicz, AJ Krętowski… - Cancers, 2022 - mdpi.com
Simple Summary This literature analysis is focused on the pleiotropic action associated with
metformin treatment. Precisely, metformin treatment exerts many health effects, mainly by …

Resveratrol as an enhancer of apoptosis in cancer: a mechanistic review

M Ashrafizadeh, S Taeb… - Anti-Cancer Agents …, 2021 - ingentaconnect.com
The resistance to therapy of cancer cells is a challenge for achieving an appropriate
therapeutic outcome. Cancer (stem) cells possess several mechanisms for increasing their …

The radioprotective effects of alpha-lipoic acid on radiotherapy-induced toxicities: a systematic review

S Sheikholeslami, S Khodaverdian, M Dorri-Giv… - International …, 2021 - Elsevier
Purpose Radiation therapy is one of the main cancer treatment modalities applied in 50–
70% of cancer patients. Despite the many advantages of this treatment, such as non …

The role of melatonin on radiation-induced pneumonitis and lung fibrosis: a systematic review

S Sheikholeslami, T Aryafar, R Abedi-Firouzjah… - Life Sciences, 2021 - Elsevier
Purpose Pneumonitis and lung fibrosis, as the most common compliances of lung
irradiation, can affect the quality of life. The use of radio-protective agents can ameliorate …

Rules of Chinese herbal intervention of radiation pneumonia based on network pharmacology and data mining

W Dan, C Wu, C Xue, J Liu, X Guo… - … and Alternative Medicine, 2022 - Wiley Online Library
Objective. To explore the mechanism and principles of traditional Chinese medicine (TCM)
in the management of radiation pneumonia. Methods. The targets of radiation pneumonia …

[HTML][HTML] Monomeric compounds from traditional Chinese medicine: New hopes for drug discovery in pulmonary fibrosis

Q Wang, W Li, H Hu, X Lu, S Qin - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Pulmonary fibrosis (PF) is a chronic and irreversible pulmonary disease, and can lead to
decreased lung function, respiratory failure and even death. The pathogenesis research and …

Metformin:(future) best friend of the radiation oncologist?

B Chevalier, D Pasquier, EF Lartigau… - Radiotherapy and …, 2020 - Elsevier
Several molecules are being investigated for their ability to enhance the anti-tumor effect of
radiotherapy. The widely prescribed antidiabetic drug metformin has been suggested to …

The effects of lipoic acid on respiratory diseases

X Guo, S Wu, J Shang, W Dong, Y Li, Q Peng… - International …, 2023 - Elsevier
Respiratory diseases, including lung cancer, pulmonary fibrosis, asthma, and the recently
emerging fatal coronavirus disease-19 (COVID-19), are the leading causes of illness and …