Treatment of heparin-induced thrombocytopenia: a critical review

J Hirsh, N Heddle, JG Kelton - Archives of internal medicine, 2004 - jamanetwork.com
Heparin-induced thrombocytopenia (HIT) is a serious complication of heparin therapy that
has a high rate of morbidity (thrombosis and amputation) and mortality. In the past, a number …

[HTML][HTML] Heparin‐induced thrombocytopenia complicating extracorporeal membrane oxygenation support: Review of the literature and alternative anticoagulants

U Pollak - Journal of Thrombosis and Haemostasis, 2019 - Elsevier
Heparin‐induced thrombocytopenia (HIT) is a life‐threatening prothrombotic, immune‐
mediated complication of unfractionated heparin and low molecular weight heparin therapy …

Delayed-onset heparin-induced thrombocytopenia

L Rice, WK Attisha, A Drexler… - Annals of internal …, 2002 - acpjournals.org
Background: Heparin-induced thrombocytopenia presents 5 to 12 days after heparin
exposure, with or without arterial or venous thromboemboli. Delayed recognition and …

Recombinant hirudin in clinical practice: focus on lepirudin

A Greinacher, N Lubenow - Circulation, 2001 - Am Heart Assoc
Clinical applications for recombinant hirudins have been investigated for the past 10 years.
The first indication for which a hirudin—lepirudin—has been approved is treatment of …

New oral anticoagulants in the treatment of heparin-induced thrombocytopenia

M Sharifi, C Bay, Z Vajo, W Freeman, M Sharifi… - Thrombosis …, 2015 - Elsevier
Background Heparin induced thrombocytopenia (HIT) is a potentially catastrophic syndrome
with a high incidence of vascular thrombosis. There are little data on the efficacy of new oral …

Heparin-induced thrombocytopenia and extracorporeal membrane oxygenation: a case report and review of the literature

U Pollak, J Yacobobich, H Tamary… - The Journal of …, 2011 - ject.edpsciences.org
Heparin-induced thrombocytopenia (HIT) is an immune-mediated coagulation side effect of
heparin therapy characterized by thrombocytopenia and by a paradoxical prothrombotic …

Heparin-induced thrombocytopenia in pediatrics

T Severin, AH Sutor - Seminars in thrombosis and hemostasis, 2001 - thieme-connect.com
As in adult patients, heparin is used for prophylaxis and treatment of thromboembolism in
newborns, children, and adolescents. Patients receiving heparin are potentially at risk to …

Diagnosis and treatment of heparin-induced thrombocytopenia in neonates and children

L Risch, AR Huber, M Schmugge - Thrombosis research, 2006 - Elsevier
Heparin-induced thrombocytopenia (HIT), a well-known side effect of heparin therapy,
occurs with an incidence of 1–2% in certain pediatric patient groups. In affected children, HIT …

Drug‐inducedand Drug‐dependent Immune Thrombocytopenias

A Greinacher, P Eichler, N Lubenow… - Reviews in Clinical and …, 2001 - Wiley Online Library
Thrombocytopenia is a frequent comorbid condition in many in hospital patients. In some
patients, drugs are the cause of low platelet counts. While cytotoxic effects of anti‐tumor …

Counteracting the effects of anticoagulants and antiplatelet agents during neurosurgical emergencies

DJ Powner, EA Hartwell, WK Hoots - Neurosurgery, 2005 - journals.lww.com
OBJECTIVE: Emergent neurosurgery may be precipitated or complicated by previous or
concomitant administration of anticoagulants, thrombolytic medications, or antiplatelet …