The epidemiology and molecular biology of colorectal cancer are reviewed with a view to
understanding their interrelationship. Risk factors for colorectal neoplasia include a positive …

Currently available evidence supports a role for the hepatitis B virus (HBV) x gene and
protein in the pathogenesis of HBV‐induced hepatocellular carcinoma (HCC). HBx gene is …

Chronic hepatitis B virus (HBV) infection is a major global cause of hepatocellular carcinoma
(HCC). Individuals who are chronic carriers have a greater than 100‐fold increased relative …

The hepatitis B virus X protein (HBx) is a broadly acting transactivator implicated in the
development of liver cancer. Recently, HBx has been reported to interact with several …

Hepatocellular carcinoma (HCC) is one of the leading causes of death induced by cancer in
the modern world and majority of the cases are related to chronic hepatitis B virus (HBV) …

It is clear that a number of host-cell factors facilitate virus replication and, conversely, a
number of other factors possess inherent antiviral activity. Research, particularly over the …

Chronic infection with hepatitis B virus (HBV) is a major risk factor for the development of
hepatocellular carcinoma (HCC). The pathogenesis of HBV‐induced malignant …

Chronic hepatitis B virus (HBV) infection puts more than 250 million people at a greatly
increased risk to develop end-stage liver disease. Like all hepadnaviruses, HBV replicates …

Hepatitis B virus is a causative agent of hepatocellular carcinoma, and in the course of
tumorigenesis, the X-gene product (HBx) is known to play important roles. Here, we …

Human hepatitis B virus (HBV) is a major risk factor of human hepatocellular carcinoma.
Both in vivo and in vitro studies have shown that HBV X protein (HBx) can bind to the p53 …