Ivermectin induces cytostatic autophagy by blocking the PAK1/Akt axis in breast cancer
Breast cancer is the most common cancer among women worldwide, yet successful
treatment remains a clinical challenge. Ivermectin, a broad-spectrum antiparasitic drug, has …
treatment remains a clinical challenge. Ivermectin, a broad-spectrum antiparasitic drug, has …
Crosstalk between autophagy and intracellular radiation response
L Hu, H Wang, L Huang, Y Zhao… - … journal of oncology, 2016 - spandidos-publications.com
Autophagy induced by radiation is critical to cell fate decision. Evidence now sheds light on
the importance of autophagy induced by cancer radiotherapy. Traditional view considers …
the importance of autophagy induced by cancer radiotherapy. Traditional view considers …
A novel cytostatic form of autophagy in sensitization of non-small cell lung cancer cells to radiation by vitamin D and the vitamin D analog, EB 1089
K Sharma, RW Goehe, X Di, MA Hicks, SV Torti… - Autophagy, 2014 - Taylor & Francis
The standard of care for unresectable lung cancer is chemoradiation. However, therapeutic
options are limited and patients are rarely cured. We have previously shown that vitamin D …
options are limited and patients are rarely cured. We have previously shown that vitamin D …
Vitamin D enhances radiosensitivity of colorectal cancer by reversing epithelial-mesenchymal transition
X Yu, Q Wang, B Liu, N Zhang… - Frontiers in Cell and …, 2021 - frontiersin.org
Colorectal cancer (CRC) is often resistant to conventional therapies. Previous studies have
reported the anticancer effects of vitamin D in several cancers, its role in radiotherapy (RT) …
reported the anticancer effects of vitamin D in several cancers, its role in radiotherapy (RT) …
Autophagy as a potential therapeutic target in breast cancer treatment
N Lisiak, E Toton, M Rybczynska - Current Cancer Drug …, 2018 - ingentaconnect.com
One of the crucial reasons of breast cancer therapy failure is an impairment of mechanisms
responsible for metabolism and cellular homeostasis, which makes it difficult to foresee the …
responsible for metabolism and cellular homeostasis, which makes it difficult to foresee the …
Immune response: a missed opportunity between vitamin D and radiotherapy
X Yu, B Liu, N Zhang, Q Wang… - Frontiers in Cell and …, 2021 - frontiersin.org
Radiotherapy (RT) is a mainstay treatment in several types of cancer and acts by mediating
various forms of cancer cell death, although it is still a large challenge to enhance therapy …
various forms of cancer cell death, although it is still a large challenge to enhance therapy …