Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …

Neurotrophins, including brain-derived neurotrophic factor (BDNF), are expressed in the
hippocampus, as well as their precursors, the pro-neurotrophins. The neurotrophins signal …

Brain-derived neurotrophic factor is an extensively studied neurotrophin implicated in the
pathology of multiple neurodegenerative and psychiatric disorders including, but not limited …

Stroke leads to long term sensory, motor and cognitive impairments. Most patients
experience some degree of spontaneous recovery which is mostly incomplete and varying …

Anxiety or depression after percutaneous coronary intervention (PCI) is one of the key
clinical problems in cardiology that need to be solved urgently. Brain-derived neurotrophic …

Background Converging lines of evidence suggest that Brain-Derived Neurotrophic Factor
(BDNF) may play a central role in the pathogenesis of Bipolar Disorder (BD), thus …

Post-stroke depression (PSD) is a neuropsychiatric affective disorder that can develop after
stroke. Patients with PSD show poorer functional and recovery outcomes than patients with …

Metabolic syndrome (MetS) is a public health problem and a risk of developing
cardiometabolic and neurodegenerative diseases. The biochemical-inflammatory …

Brain-derived neurotrophic factor (BDNF) is a crucial neurotrophic factor adding to neurons'
development and endurance. The amount of BDNF present in the brain determines …

Brain-derived neurotrophic factor (BDNF), its precursor proBDNF, BDNF pro-peptide, BDNF
mRNA levels, as well as TrkB and p75 NTR receptors mRNA and protein levels, were …