It has been known for a long time that thyroid hormones have prominent effects on hepatic
fatty acid and cholesterol synthesis and metabolism. Indeed, hypothyroidism has been …

One of the most compelling features of dry eye disease (DED) is that it occurs more
frequently in women than men. In fact, the female sex is a significant risk factor for the …

The development of the mammalian cerebellum is orchestrated by both cell-autonomous
programs and inductive environmental influences. Here, we describe the main processes of …

Cardiac hypertrophy can be defined as an increase in heart mass. Pathological cardiac
hypertrophy (heart growth that occurs in settings of disease, eg hypertension) is a key risk …

Thyroid hormones (THs) play critical roles in the differentiation, growth, metabolism, and
physiological function of virtually all tissues. TH binds to receptors that are ligand …

Life history theory seeks to explain the evolution of the major features of life cycles by
analyzing the ecological factors that shape age-specific schedules of growth, reproduction …

The hypothalamus‐pituitary‐thyroid (HPT) axis determines the set point of thyroid hormone
(TH) production. Hypothalamic thyrotropin‐releasing hormone (TRH) stimulates the …

The heart is a major target organ for thyroid hormone action, and marked changes occur in
cardiac function in patients with hypo-or hyperthyroidism. T3-induced changes in cardiac …

The thyroid hormones (THs), thyroxine (T4) and triiodothyronine (T3) are products of the
thyroid gland in all vertebrates. Their role in early development and metamorphosis is well …

During the last few decades our understanding of the possible role of thyroid hormones
during brain development has increased and contributed to resolve previously discordant …