Present status of microfluidic PCR chip in nucleic acid detection and future perspective

S Chen, Y Sun, F Fan, S Chen, Y Zhang… - TrAC Trends in …, 2022 - Elsevier
Polymerase chain reaction (PCR) amplifies specific fragment of DNA molecules and has
been extensively applied in fields of pathogens and gene mutation detection, food safety …

[HTML][HTML] Development of glass-based microfluidic devices: A review on its fabrication and biologic applications

S Aralekallu, R Boddula, V Singh - Materials & Design, 2023 - Elsevier
The advent of glass-based microfluidic devices further revolutionized in microfluidic
technology due to the several advantageous properties in terms of photonics, electronics …

Microfluidic lab-on-a-chip platforms: requirements, characteristics and applications

D Mark, S Haeberle, G Roth, F Von Stetten… - Microfluidics based …, 2010 - Springer
This review summarizes recent developments in microfluidic platform approaches. In
contrast to isolated application-specific solutions, a microfluidic platform provides a set of …

Rapid prototyping of microfluidic systems in poly (dimethylsiloxane)

DC Duffy, JC McDonald, OJA Schueller… - Analytical …, 1998 - ACS Publications
This paper describes a procedure that makes it possible to design and fabricate (including
sealing) microfluidic systems in an elastomeric material poly (dimethylsiloxane)(PDMS) in …

Microfluidics: Fluid physics at the nanoliter scale

TM Squires, SR Quake - Reviews of modern physics, 2005 - APS
Microfabricated integrated circuits revolutionized computation by vastly reducing the space,
labor, and time required for calculations. Microfluidic systems hold similar promise for the …

Soft lithography in biology and biochemistry

GM Whitesides, E Ostuni, S Takayama… - Annual review of …, 2001 - annualreviews.org
▪ Abstract Soft lithography, a set of techniques for microfabrication, is based on printing and
molding using elastomeric stamps with the patterns of interest in bas-relief. As a technique …

Physics and applications of microfluidics in biology

DJ Beebe, GA Mensing… - Annual review of …, 2002 - annualreviews.org
▪ Abstract Fluid flow at the microscale exhibits unique phenomena that can be leveraged to
fabricate devices and components capable of performing functions useful for biological …

A review of micropumps

DJ Laser, JG Santiago - Journal of micromechanics and …, 2004 - iopscience.iop.org
We survey progress over the past 25 years in the development of microscale devices for
pumping fluids. We attempt to provide both a reference for micropump researchers and a …

Micro total analysis systems. 1. Introduction, theory, and technology

DR Reyes, D Iossifidis, PA Auroux, A Manz - Analytical chemistry, 2002 - ACS Publications
The area of micro total analysis systems, also called “lab on a chip”, or miniaturized analysis
systems, is growing rapidly. Since the excellent research documented in many publications …

Control and detection of chemical reactions in microfluidic systems

AJ Demello - Nature, 2006 - nature.com
Recent years have seen considerable progress in the development of microfabricated
systems for use in the chemical and biological sciences. Much development has been …