Background Due the computational complexity of sequence alignment algorithms, various
accelerated solutions have been proposed to speedup this analysis. NVBIO is the only …

Genomic similarity is a key metric in genomics, used in important tasks such as genome
clustering and metagenomic profiling. One commonly-used approach is to treat each …

Background Pairwise sequence alignment is widely used in many biological tools and
applications. Existing GPU accelerated implementations mainly focus on calculating optimal …

Abstract Background In Overlap-Layout-Consensus (OLC) based de novo assembly, all
reads must be compared with every other read to find overlaps. This makes the process …

Genomic analysis is the study of genes which includes the identification, measurement, or
comparison of genomic features. Genomics research is of great importance to our society …

The efficient computation of Beta distribution functions, particularly the Probability Density
Function (PDF) and Cumulative Distribution Function (CDF), is critical in various scientific …

Heterogeneous systems are becoming increasingly relevant, due to their performance and
energy efficiency capabilities, being present in all types of computing platforms, from …

The seeding heuristic is widely used in many DNA analysis applications to speed up the
analysis time. In many applications, seeding takes a substantial amount of the total …

The rising popularity of renewable energy sources requires advanced, efficient power
electronic systems for energy conversion, grid integration, and system management, thereby …

De novo genome assembly reconstructs the chromosomes from massive relatively short
fragmented reads and serves as fundamental for studying new species where there is no …