Helicobacter pylori treatment in the era of increasing antibiotic resistance

DY Graham, L Fischbach - Gut, 2010 - gut.bmj.com
With few exceptions, the most commonly recommended triple Helicobacter pylori regimen
(proton pump inhibitor (PPI), amoxicillin and clarithromycin) now provides unacceptably low …

Global eradication rates for Helicobacter pylori infection: systematic review and meta-analysis of sequential therapy

L Gatta, N Vakil, D Vaira, C Scarpignato - Bmj, 2013 - bmj.com
Objective To do a systematic review and meta-analysis of studies comparing sequential
therapy for eradication of Helicobacter pylori with pre-existing and new therapies, thus …

Optimum duration of regimens for Helicobacter pylori eradication

Y Yuan, AC Ford, KJ Khan, JP Gisbert… - Cochrane Database …, 2013 - cochranelibrary.com
Background The optimal duration for Helicobacter pylori (H. pylori) eradication therapy is
controversial, with recommendations ranging from 7 to 14 days. Several systematic reviews …

A Report Card to Grade Helicobacter pylori Therapy

DY Graham, H Lu, Y Yamaoka - Helicobacter, 2007 - Wiley Online Library
Helicobacter pylori causes a serious bacterial infectious disease, and the expectations of
therapy should reflect this fact. Increasing antibiotic resistance, especially to clarithromycin …

Sequential Therapy or Triple Therapy forHelicobacter pyloriInfection: Systematic Review and Meta-Analysis of Randomized Controlled Trials in Adults and Children

L Gatta, N Vakil, G Leandro, F Di Mario… - Official journal of the …, 2009 - journals.lww.com
OBJECTIVES: Eradication rates with triple therapy (TT) forHelicobacter pyloriinfection have
declined to unacceptable levels. Sequential therapy (ST) is a novel treatment that has …

Meta-analysis: Sequential Therapy Appears Superior to Standard Therapy for Helicobacter pylori Infection in Patients Naive to Treatment

NS Jafri, CA Hornung, CW Howden - Annals of internal medicine, 2008 - acpjournals.org
Background: Standard proton-pump inhibitor–based therapy for Helicobacter pylori infection
fails in up to one quarter of patients. Sequential therapy may be more efficacious. Purpose …

Eradication therapy for Helicobacter pylori

N Vakil, F Megraud - Gastroenterology, 2007 - Elsevier
Eradication therapy for Helicobacter pylori is recommended in a number of clinical
conditions. In this article, we discuss the epidemiology and cellular mechanisms that result …

The sequential therapy regimen for Helicobacter pylori eradication: a pooled-data analysis

A Zullo, V De Francesco, C Hassan, S Morini, D Vaira - Gut, 2007 - gut.bmj.com
Background:: Standard triple therapies are the most used treatment in clinical practice.
However, a critical fall in the H pylori eradication rate following these therapies has been …

Sequential therapy for Helicobacter pylori eradication: a critical review

JP Gisbert, X Calvet, A O'Connor… - Journal of clinical …, 2010 - journals.lww.com
Sequential Therapy for Helicobacter pylori Eradication: A Cr... : Journal of Clinical
Gastroenterology Sequential Therapy for Helicobacter pylori Eradication: A Critical Review …

Clarithromycin-Resistant Genotypes and Eradication of Helicobacter pylori

V De Francesco, M Margiotta, A Zullo… - Annals of internal …, 2006 - acpjournals.org
Background: Three point mutations (A2143G, A2142G, and A2142C) have been involved in
Helicobacter pylori clarithromycin resistance. Objective: To compare the eradication rates …