Prevention of aggregation and renaturation of carbonic anhydrase via weak association with octadecyl-or azobenzene-modified poly (acrylate) derivatives
The prevention of aggregation during renaturation of urea-denatured carbonic anhydrase B
(CAB) via hydrophobic and Coulomb association with anionic polymers was studied in …
(CAB) via hydrophobic and Coulomb association with anionic polymers was studied in …
Role of smart polymers in protein purification and refolding
Affinity precipitation is a non-chromatographic method which is useful for purification and
refolding of proteins. Quite often, a stimuli-sensitive polymer can be identified which …
refolding of proteins. Quite often, a stimuli-sensitive polymer can be identified which …
One-Step production of bioactive proteins through simultaneous PEGylation and refolding
J Niu, Y Zhu, L Song, Y Xie, Y Zhang… - Bioconjugate …, 2014 - ACS Publications
Production of protein therapeutics often involves in vitro refolding from bacterial inclusion
bodies and subsequent PEGylation to improve protein stability and plasma half-life. Here …
bodies and subsequent PEGylation to improve protein stability and plasma half-life. Here …
Colloidal stability and folding of antibodies in the presence of chaperone-like poly (acrylate) derivatives: role of hydrophobic and electrostatic interactions
N Martin - 2014 - theses.hal.science
Antibodies constitute the fastest growing class of human biopharmaceuticals. The
development of these engineered proteins is yet hampered by their natural propensity …
development of these engineered proteins is yet hampered by their natural propensity …