Viral vectored vaccines: design, development, preventive and therapeutic applications in human diseases

S Wang, B Liang, W Wang, L Li, N Feng… - Signal transduction and …, 2023 - nature.com
Human diseases, particularly infectious diseases and cancers, pose unprecedented
challenges to public health security and the global economy. The development and …

[HTML][HTML] Molecular breeding of livestock for disease resistance

F Gao, P Li, Y Yin, X Du, G Cao, S Wu, Y Zhao - Virology, 2023 - Elsevier
Animal infectious diseases pose a significant threat to the global agriculture and
biomedicine industries, leading to significant economic losses and public health risks. The …

Pathogenesis of Senecavirus A infection in finishing pigs

LR Joshi, MHV Fernandes… - Journal of general …, 2016 - microbiologyresearch.org
Senecavirus A (SVA) is an emerging picornavirus that has been associated with vesicular
disease and neonatal mortality in swine. Many aspects of SVA infection biology and …

Development of a blocking enzyme-linked immunosorbent assay for detection of antibodies against African swine fever virus

F Yuan, V Petrovan, LG Gimenez-Lirola, JJ Zimmerman… - Pathogens, 2021 - mdpi.com
The incursion of African swine fever virus (ASFV) into Eurasia presents a threat to the world's
swine industry. Highly sensitive and specific diagnostic assays are urgently needed for rapid …

Adaptive immune responses following Senecavirus A infection in pigs

MF Maggioli, S Lawson, M de Lima, LR Joshi… - Journal of …, 2018 - Am Soc Microbiol
Senecavirus A (SVA), an emerging picornavirus of swine, causes vesicular disease (VD)
that is clinically indistinguishable from foot-and-mouth disease (FMD) in pigs. Many aspects …

Construction of eGFP-tagged Senecavirus A for facilitating virus neutralization test and antiviral assay

F Liu, Y Huang, Q Wang, H Shan - Viruses, 2020 - mdpi.com
Senecavirus A (SVA), also known as Seneca Valley virus, is an emerging virus that causes
vesicular disease in pigs. This virus belongs to the genus Senecavirus in the family …

Persistent infection and transmission of Senecavirus A from carrier sows to contact piglets

MF Maggioli, MHV Fernandes, LR Joshi… - Journal of …, 2019 - Am Soc Microbiol
Senecavirus A (SVA) is a picornavirus that causes acute vesicular disease (VD), that is
clinically indistinguishable from foot-and-mouth disease (FMD), in pigs. Notably, SVA RNA …

Stability of Senecavirus A in animal feed ingredients and infection following consumption of contaminated feed

L C. Caserta, JC G. Noll, A Singrey… - Transboundary and …, 2022 - Wiley Online Library
Animal feed and feed ingredients have recently been investigated as sources of pathogen
introduction to farms and as a potential source of infection to animals post‐consumption of …

Senecavirus-specific recombination assays reveal the intimate link between polymerase fidelity and RNA recombination

C Li, H Wang, J Shi, D Yang, G Zhou, J Chang… - Journal of …, 2019 - Am Soc Microbiol
Senecavirus A (SVA) is a reemerging virus, and recent evidence has emphasized the
importance of SVA recombination in vivo on virus evolution. In this study, we report the …

Identification of potential novel B-cell epitopes of capsid protein VP2 in Senecavirus A

Y Ru, R Hao, C Wu, Y Li, B Lu, H Liu, H Tian… - Microbiology …, 2023 - Am Soc Microbiol
Senecavirus A (SVA) is a type of nonenveloped single-stranded, positive-sense RNA virus.
The VP2 protein is a structural protein that plays an important role in inducing early and late …