Morphogenetic fields are among the most fundamental concepts of embryology. However,
they are also among the most ill‐defined, since they consist of dynamic regulatory processes …

Development is regulated by dynamic patterns of gene expression, which are orchestrated
through the action of complex gene regulatory networks (GRNs). Substantial progress has …

Developing embryos exhibit a robust capability to reduce phenotypic variations that occur
naturally or as a result of experimental manipulation. This reduction in variation occurs by an …

Here we present a quantitative and predictive model of the transcriptional readout of the
proximal 1.7 kb of the control region of the Drosophila melanogaster gene even skipped …

Here we characterize the expression of the full system of genes which control the
segmentation morphogenetic field of Drosophila at the protein level in one dimension. The …

A fundamental problem in functional genomics is to determine the structure and dynamics of
genetic networks based on expression data. We describe a new strategy for solving this …

The datasets on gene expression are the valuable source of information about the functional
state of an organism. Recently, we have acquired the large dataset on expression of …

Background To model and thoroughly understand animal transcription networks, it is
essential to derive accurate spatial and temporal descriptions of developing gene …

Cooperative interactions by DNA-binding proteins have been implicated in cell-fate
decisions in a variety of organisms. To date, however, there are few examples in which the …

Understanding the complex regulatory networks underlying development and evolution of
multi-cellular organisms is a major problem in biology. Computational models can be used …