Antidiabetic drug sitagliptin blocks cyclophosphamide cerebral neurotoxicity by activating Nrf2 and suppressing redox cycle imbalance, inflammatory iNOS/NO/NF-κB …

AC Famurewa, NT Asogwa, SC Ezea - International Immunopharmacology, 2023 - Elsevier
Cyclophosphamide (CYP) is a classic DNA-interacting anticancer agent with broad
application in chemotherapy. However, CYP cerebral neurotoxicity is a worrisome side effect …

Cardio-Oncology and Heart Failure: A Scientific Statement from the Heart Failure Society of America

MW Bloom, JB Vo, JE Rogers, A Ferrari, A Nohria… - Journal of cardiac …, 2024 - Elsevier
Heart failure and cancer remain two of the leading causes of morbidity and mortality and the
two disease entities are linked in a complex manner. Patients with cancer are at increased …

[PDF][PDF] Recent findings of cardiac dysfunction and anti-cancer therapy

J Papierkowska, W Gawelczyk… - Medical Journal of Cell …, 2024 - sciendo.com
Cardiovascular diseases and carcer have a lot of things in common. Both of those conditions
are responsible for most deaths in first world countries. Moreover, considerable amount of …