Array‐based “Chemical Nose” sensing in diagnostics and drug discovery

Y Geng, WJ Peveler, VM Rotello - … Chemie International Edition, 2019 - Wiley Online Library
Array‐based sensor “chemical nose/tongue” platforms are inspired by the mammalian
olfactory system. Multiple sensor elements in these devices selectively interact with target …

Molecules that generate fingerprints: A new class of fluorescent sensors for chemical biology, medical diagnosis, and cryptography

L Motiei, D Margulies - Accounts of Chemical Research, 2023 - ACS Publications
Conspectus Fluorescent molecular sensors, often referred to as “turn-on” or “turn-off”
fluorescent probes, are synthetic agents that change their fluorescence signal in response to …

Real-time tracking and in vivo visualization of β-galactosidase activity in colorectal tumor with a ratiometric near-infrared fluorescent probe

K Gu, Y Xu, H Li, Z Guo, S Zhu, S Zhu… - Journal of the …, 2016 - ACS Publications
Development of “smart” noninvasive bioimaging probes for trapping specific enzyme
activities is highly desirable for cancer therapy in vivo. Given that β-galactosidase (β-gal) is …

Selectivity and specificity: pros and cons in sensing

WJ Peveler, M Yazdani, VM Rotello - ACS sensors, 2016 - ACS Publications
Sensing using specific and selective receptors provides two very different but
complementary strategies. This Sensor Issues article will discuss the merits and challenges …

Analyzing amyloid beta aggregates with a combinatorial fluorescent molecular sensor

J Hatai, L Motiei, D Margulies - Journal of the American Chemical …, 2017 - ACS Publications
Different amyloid beta (Aβ) aggregates can be discriminated by a combinatorial fluorescent
molecular sensor. The unique optical fingerprints generated by the unimolecular analytical …

Protein recognition by a pattern-generating fluorescent molecular probe

Z Pode, R Peri-Naor, JM Georgeson, T Ilani… - Nature …, 2017 - nature.com
Fluorescent molecular probes have become valuable tools in protein research; however, the
current methods for using these probes are less suitable for analysing specific populations …

In situ visualizable self-assembly, aggregation-induced emission and circularly polarized luminescence of tetraphenylethene and alanine-based chiral polytriazole

Q Liu, Q Xia, S Wang, BS Li, BZ Tang - Journal of Materials Chemistry …, 2018 - pubs.rsc.org
This work provides a novel strategy for the construction and characterization of novel
luminescent nano/micro architectures and functional thin solid films at the macroscale of …

Tuning the anion binding properties of lanthanide receptors to discriminate nucleoside phosphates in a sensing array

SH Hewitt, G Macey, R Mailhot, MRJ Elsegood… - Chemical …, 2020 - pubs.rsc.org
The development of synthetic receptors for the selective binding and discrimination of
anions in water requires an understanding of how anions interact with these synthetic …

Application of chemometrics in biosensing: A brief review

E Martynko, D Kirsanov - Biosensors, 2020 - mdpi.com
The field of biosensing is rapidly developing, and the number of novel sensor architectures
and different sensing elements is growing fast. One of the most important features of all …

Circularly Polarized Luminescence and Tunable Helical Assemblies of Aggregation-Induced Emission Amphiphilic Polytriazole Carrying Chiral l-Phenylalanine …

Q Liu, Q Xia, Y Xiong, BS Li, BZ Tang - Macromolecules, 2020 - ACS Publications
Chiral polytriazole derivatives carrying teraphenylethene (TPE) and l-phenylalanine were
synthesized, which had a TPE backbone and a chiral l-phenylalanine pendant in common …