An early set of blastomere specifications occurs during cleavage in the sea urchin embryo,
the result of both conditional and autonomous processes, as proposed in the model for this …

Evolution is of interest not only to developmental biology but also to genetics and genomics.
We are witnessing a new era in which evolution, development, genetics and genomics are …

Gene regulatory networks are the most complex, extensive control systems found in nature.
The interaction between biology and evolution has been the subject of great interest in …

The otd/Otx gene family encodes paired-like homeodomain proteins that are involved in the
regulation of anterior head structure and sensory organ development. Using the yeast one …

ABSTRACT β-catenin is thought to mediate cell fate specification events by localizing to the
nucleus where it modulates gene expression. To ask whether β-catenin is involved in cell …

The human oncogene β-catenin is a bifunctional protein with critical roles in both cell
adhesion and transcriptional regulation in the Wnt pathway,,. Wnt/β-catenin signalling has …

Micromeres and their immediate descendants have three known developmental functions in
regularly developing sea urchins: immediately after their initial segregation, they are the …

Cell-cell interactions are thought to regulate the differential specification of secondary
mesenchyme cells (SMCs) and endoderm in the sea urchin embryo. The molecular bases of …

The entry of β‐catenin into vegetal cell nuclei beginning at the 16‐cell stage is one of the
earliest known molecular asymmetries seen along the animal–vegetal axis in the sea urchin …

New secondary mesenchyme specific genes, expressed exclusively in pigment cells, were
isolated from sea urchin embryos using a differential screening of a macroarray cDNA …