Paradigms of dynamic control of thyroid hormone signaling

AC Bianco, A Dumitrescu, B Gereben… - Endocrine …, 2019 - academic.oup.com
Thyroid hormone (TH) molecules enter cells via membrane transporters and, depending on
the cell type, can be activated (ie, T4 to T3 conversion) or inactivated (ie, T3 to 3, 3′-diiodo-l …

Radioiodine therapy in benign thyroid diseases: effects, side effects, and factors affecting therapeutic outcome

SJ Bonnema, L Hegedüs - Endocrine reviews, 2012 - academic.oup.com
Radioiodine (131I) therapy of benign thyroid diseases was introduced 70 yr ago, and the
patients treated since then are probably numbered in the millions. Fifty to 90% of …

Mesenchymal stem cell-based therapy for stroke: current understanding and challenges

W Li, L Shi, B Hu, Y Hong, H Zhang, X Li… - Frontiers in Cellular …, 2021 - frontiersin.org
Stroke, the most prevalent cerebrovascular disease, causes serious loss of neurological
function and is the leading cause of morbidity and mortality worldwide. Despite advances in …

Thyroid hormones in the brain and their impact in recovery mechanisms after stroke

D Talhada, CRA Santos, I Gonçalves… - Frontiers in …, 2019 - frontiersin.org
Thyroid hormones are of fundamental importance for brain development and essential
factors to warrant brain functions throughout life. Their actions are mediated by binding to …

Ischemia‐induced changes in glucagon‐like peptide‐1 receptor and neuroprotective effect of its agonist, exendin‐4, in experimental transient cerebral ischemia

C Hyun Lee, B Yan, KY Yoo, JH Choi… - Journal of …, 2011 - Wiley Online Library
Abstract Glucagon‐like peptide‐1 receptor (GLP‐1R) protects against neuronal damages in
the brain. In the present study, ischemia‐induced changes in GLP‐1R immunoreactivity in …

The anti-amnesic effects of luteolin against amyloid β25–35 peptide-induced toxicity in mice involve the protection of neurovascular unit

R Liu, M Gao, GF Qiang, TT Zhang, X Lan, J Ying… - Neuroscience, 2009 - Elsevier
Luteolin (3′, 4′, 5, 7-tetrahydroxyflavone) is an important member of the flavonoid family. It
exhibits strongly anti-inflammatory, antioxidant and phytoestrogen-like activities. In the …

Curcuma oil: reduces early accumulation of oxidative product and is anti-apoptogenic in transient focal ischemia in rat brain

P Rathore, P Dohare, S Varma, A Ray, U Sharma… - Neurochemical …, 2008 - Springer
Turmeric is a source of numerous aromatic compounds isolated from powdered rhizomes of
Curcuma longa Linn. The constituents are present as volatile oil, the Curcuma oil (C. oil) …

Neuroprotective efficacy and therapeutic window of curcuma oil: in rat embolic stroke model

P Dohare, P Garg, U Sharma, NR Jagannathan… - … and alternative medicine, 2008 - Springer
Background Among the naturally occurring compounds, turmeric from the dried rhizome of
the plant Curcuma longa has long been used extensively as a condiment and a household …

Comparison of the detrimental features of microglia and infiltrated macrophages in traumatic brain injury: a study using a hypnotic bromovalerylurea

N Abe, ME Choudhury, M Watanabe, S Kawasaki… - Glia, 2018 - Wiley Online Library
Microglia and blood‐borne macrophages in injured or diseased brains are difficult to
distinguish because they share many common characteristics. However, the identification of …

The effects of Nigella sativa extract on hypothyroidism-associated learning and memory impairment during neonatal and juvenile growth in rats

F Beheshti, M Hosseini, MN Shafei… - Nutritional …, 2017 - Taylor & Francis
Objectives: It has been shown that hypothyroidism-induced oxidative damage in brain tissue
is involved in its adverse effects on learning and memory. Nigella sativa (N. sativa) has been …