Eryptosis: programmed death of nucleus-free, iron-filled blood cells

P Dreischer, M Duszenko, J Stein, T Wieder - Cells, 2022 - mdpi.com
Human erythrocytes are organelle-free cells packaged with iron-containing hemoglobin,
specializing in the transport of oxygen. With a total number of approximately 25 trillion cells …

Casein kinase 1α mediates eryptosis: a review

A Tkachenko, A Onishchenko - Apoptosis, 2023 - Springer
Eryptosis is a coordinated non-lytic cell death of erythrocytes characterized by cell
shrinkage, cell membrane scrambling, Ca2+ influx, ceramide accumulation, oxidative stress …

Apoptosis and eryptosis: similarities and differences

A Tkachenko - Apoptosis, 2024 - Springer
Eryptosis is a regulated cell death (RCD) of mature erythrocytes initially described as a
counterpart of apoptosis for enucleated cells. However, over the recent years, a growing …

Marine Polysaccharides Carrageenans Enhance Eryptosis and Alter Lipid Order of Cell Membranes in Erythrocytes

V Prokopiuk, A Onishchenko, L Tryfonyuk… - Cell Biochemistry and …, 2024 - Springer
Aim In the current study, hemocompatibility of three major commercially available types of
carrageenans (ι, κ and λ) was investigated focusing on eryptosis. Materials and methods …

Epidemic dropsy toxin, sanguinarine chloride, stimulates sucrose-sensitive hemolysis and breakdown of membrane phospholipid asymmetry in human erythrocytes

MA Alfhili, J Alsughayyir, AB Basudan - Toxicon, 2021 - Elsevier
Sanguinarine (SGN) is a benzophenathridine alkaloid extracted from Sanguinaria
canadensis plant. SGN is incriminated in epidemic dropsy (ED) characterized by multiple …

Do Marine Polysaccharides Carrageenans Modulate Non-apoptotic Regulated Cell Deaths?(a Review)

A Tkachenko, A Onishchenko, V Prokopiuk - Current Pharmacology …, 2023 - Springer
Purpose of Review A growing number of studies indicate that a network of regulated cell
death (RCD) pathways plays a vital role in tumorigenesis suggesting its targeting to be a …

Hemocompatibility studies in nanotoxicology: Hemolysis or eryptosis?(A review)

A Tkachenko - Toxicology in Vitro, 2024 - Elsevier
Hemocompatibility evaluation is an important step in nanotoxicological studies. It is
generally accepted that nanomaterials promote lysis of erythrocytes, blood clotting, alter …

[HTML][HTML] Elucidation of the Active Agents in a West African Ground Herbal Medicine Formulation That Elicit Antimalarial Activities in In Vitro and In Vivo Models

S Owumi, JO Olanlokun, B Wu, AM Duro-Ladipo… - Molecules, 2024 - mdpi.com
Agunmu (ground herbal medicine) is a form of West African traditional medicine consisting
of a cocktail of herbs. The goal of this study is to evaluate a formulation of Agunmu made …

Red Blood Cell BCL-xL Is Required for Plasmodium falciparum Survival: Insights into Host-Directed Malaria Therapies

C Boulet, G Siddiqui, TL Gaynor, C Doerig, DJ Creek… - Microorganisms, 2022 - mdpi.com
The development of antimalarial drug resistance is an ongoing problem threatening
progress towards the elimination of malaria, and antimalarial treatments are urgently …

Therapeutic efficacy of candidate antischistosomal drugs in a murine model of schistosomiasis mansoni

OS Mohammad, HM Hussein, SW Abdel-Sayed… - Parasitology …, 2024 - Springer
Schistosomiasis is a neglected tropical disease associated with considerable morbidity.
Praziquantel (PZQ) is effective against adult schistosomes, yet, it has little effect on juvenile …