The neuropsychiatry of Parkinson's disease: advances and challenges

D Weintraub, D Aarsland, KR Chaudhuri… - The Lancet …, 2022 - thelancet.com
In people with Parkinson's disease, neuropsychiatric signs and symptoms are common
throughout the disease course. These symptoms can be disabling and as clinically relevant …

[HTML][HTML] Prevalence and clinical aspects of depression in Parkinson's disease: a systematic review and meta‑analysis of 129 studies

S Cong, C Xiang, S Zhang, T Zhang, H Wang… - … & Biobehavioral Reviews, 2022 - Elsevier
Depression is one of the most important non-motor symptoms in Parkinson's disease (PD),
but its prevalence and related clinical characteristics are unclear. To this end, we performed …

Depression in dementia with Lewy bodies: a critical update

KA Jellinger - Journal of Neural Transmission, 2023 - Springer
Depression with an estimated prevalence of 35% is a frequent manifestation of dementia
with Lewy bodies (DLB), having negative effects on cognitive performance and life …

[HTML][HTML] Older adults respond better to psychological therapy than working-age adults: evidence from a large sample of mental health service attendees.

R Saunders, JEJ Buckman, J Stott, J Leibowitz… - Journal of affective …, 2021 - Elsevier
Background Older adults commonly experience depression and anxiety, yet are under-
represented in psychological treatment services. There is uncertainty about the outcomes …

The pathobiological basis of depression in Parkinson disease: challenges and outlooks

KA Jellinger - Journal of neural transmission, 2022 - Springer
Depression, with an estimated prevalence of about 40% is a most common neuropsychiatric
disorder in Parkinson disease (PD), with a negative impact on quality of life, cognitive …

Differences in gut microbiota correlate with symptoms and regional brain volumes in patients with late-life depression

CF Tsai, CH Chuang, YP Wang, YB Lin… - Frontiers in Aging …, 2022 - frontiersin.org
Depression is associated with gut dysbiosis that disrupts a gut-brain bidirectional axis. Gray
matter volume changes in cortical and subcortical structures, including prefrontal regions …

Prodromal dementia with Lewy bodies: evolution of symptoms and predictors of dementia onset

KA Wyman-Chick, LR O'Keefe… - Journal of geriatric …, 2022 - journals.sagepub.com
Background: Research criteria for prodromal dementia with Lewy bodies (DLB) were
published in 2020, but little is known regarding prodromal DLB in clinical settings. Methods …

Imaging dopaminergic neurotransmission in neurodegenerative disorders

ED Wallert, E van de Giessen, RJJ Knol… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Imaging of dopaminergic transmission in neurodegenerative disorders such as Parkinson
disease (PD) or dementia with Lewy bodies plays a major role in clinical practice and in …

Towards an understanding of the pathological basis of senile depression and incident dementia: Implications for treatment

I Kawakami, J Iga, S Takahashi, YT Lin… - Psychiatry and …, 2022 - Wiley Online Library
Senile depression (SD) is a heterogeneous syndrome. Several clinical profiles are more
likely to appear in SD than in early‐life depression, but it remains unclear whether the …

Molecular Imaging in Parkinsonian Disorders—What's New and Hot?

S Prange, H Theis, M Banwinkler, T van Eimeren - Brain Sciences, 2022 - mdpi.com
Highlights Imaging of the dopamine transporter (DAT)(in particular using 11C-or 18F-PE2I)
most reliably and precisely measures neurodegeneration of the dopaminergic system in …