Leukemia is a common and lethal disease. In recent years, iron-based nanomedicines have
been developed as a new ferroptosis inducer to leukemia. However, the cytotoxicity of iron …

Background Ovarian cancer is a common gynecological malignant disease in women. Our
work aimed to study the specific functions of ZNF252P antisense RNA 1 (ZNF252P-AS1) in …

Background Lung adenocarcinoma (LUAD) is the most common pathology subtype of lung
cancer. In recent years, immunotherapy, targeted therapy and chemotherapeutics conferred …

Simple Summary This study used two different syngeneic mouse mammary tumor models to
determine the effect of a small molecule NSC243928 on intra-tumoral immune cells. We …

Abstract Lymphocyte antigen 6K (LY6K) is a small GPI-linked protein that is normally
expressed in testes. Increased expression of LY6K is significantly associated with poor …

Adoptive T cell-receptor therapy (ACT) could represent a promising approach in the targeted
treatment of epithelial ovarian cancer (EOC). However, the identification of suitable tumor …

Purpose The aim of this study is to delve into the value of N6-Methyladenosine (m6A)-
associated genes (MAGs) in pancreatic cancer (PC) prognosis. Methods PC sequencing …

Background Pancreatic ductal adenocarcinoma (PDAC) has a heterogeneous make-up of
myeloid cells that influences the therapeutic response and prognosis. However …

Small molecule NSC243928 binds with LY6K, a potential target for the treatment of triple-
negative breast cancer, and induces cancer cell death with an unclear mechanism. We have …

Background Genomic instability (GI) is an effective prognostic marker of cancer. Thus, in this
work, we aimed to explore the impact of GI derived signature on prognosis in non-small cell …