Mitochondria are cellular organelles responsible for generation of chemical energy in the
process called oxidative phosphorylation. They originate from a bacterial ancestor and …

The mitochondrial genome encodes core subunits of the respiratory chain that drives
oxidative phosphorylation and is, therefore, essential for energy conversion. Advances in …

Mitochondrial ribosomes (mitoribosomes) are tethered to the mitochondrial inner membrane
to facilitate the cotranslational membrane insertion of the synthesized proteins. We report …

Mitoribosomes are essential for the synthesis and maintenance of bioenergetic proteins.
Here we use cryo-electron microscopy to determine a series of the small mitoribosomal …

Mitochondria are one of the most important organelles in cells. Mitochondria are semi-
autonomous organelles with their own genetic system, and can independently replicate …

Mitochondrial ribosomes (mitoribosomes) synthesize proteins encoded within the
mitochondrial genome that are assembled into oxidative phosphorylation complexes. Thus …

During translation, a conserved GTPase elongation factor—EF-G in bacteria or eEF2 in
eukaryotes—translocates tRNA and mRNA through the ribosome. EF-G has been proposed …

Mitochondria contain dedicated ribosomes (mitoribosomes), which synthesize the
mitochondrial-encoded core components of the oxidative phosphorylation complexes. The …

Ribosome biogenesis requires auxiliary factors to promote folding and assembly of
ribosomal proteins and RNA. Particularly, maturation of the peptidyl transferase center (PTC) …

Mitochondria are the powerhouse of eukaryotic cells. They possess their own gene
expression machineries where highly divergent and specialized ribosomes, named …