Macrophage, as an integral component of the immune system and the first responder to
local damage, is on the front line of defense against infection. Over the past century, the …

Alveolar macrophages have been investigated for years by approaches involving
macrophage extraction from the lung by bronchoalveolar lavage, or by cell removal from …

The lung is continuously exposed to potentially hazardous environmental challenges in the
form of inert material and microbes. Pulmonary macrophages are critical in maintaining a …

Paradoxically, early host responses to infection include the upregulation of the
antiphagocytic molecule, CD47. This suggests that CD47 blockade could enhance antigen …

Increasing evidence shows that antigen-presenting cells (APCs) are involved in the
development of inflammation associated to hypertension. However, the potential role of …

Langerin is a C‐type lectin receptor that is expressed on Langerhans cells and langerin‐
positive dermal dendritic cells in the skin. Little is known about the function of langerin+ cells …

Plasmacytoid dendritic cells (pDCs), which are prominent type I interferon (IFN-I)-producing
immune cells, have been extensively implicated in systemic lupus erythematosus (SLE) …

Neutrophils orchestrate the innate immune response against microorganisms and are
increasingly recognized to modulate cancer development in primary tumors and metastases …

Hematopoietic stem cell (HSC) multipotency and self-renewal are typically defined through
serial transplantation experiments. Host conditioning is necessary for robust HSC …

Acute respiratory distress syndrome (ARDS) is one of the most devastating complications of
sepsis lacking of effective therapy. Mitochondrial dynamics undergoing continuous fusion …