Mechanisms of T‐cell immunosuppression by mesenchymal stromal cells: What do we know so far?

R Haddad, F Saldanha-Araujo - BioMed research international, 2014 - Wiley Online Library
Mesenchymal stromal cells (MSCs) are multipotent cells, which can give rise to several cell
types including osteoblasts, adipocytes, and chondroblasts. These cells can be found in a …

Large‐scale expansion of human mesenchymal stem cells

MNFB Hassan, MD Yazid, MHM Yunus… - Stem Cells …, 2020 - Wiley Online Library
Mesenchymal stem cells (MSCs) are multipotent stem cells with strong immunosuppressive
property that renders them an attractive source of cells for cell therapy. MSCs have been …

Highly elastic, electroconductive, immunomodulatory graphene crosslinked collagen cryogel for spinal cord regeneration

G Agarwal, N Kumar, A Srivastava - Materials Science and Engineering: C, 2021 - Elsevier
Novel amino-functionalized graphene crosslinked collagen based nerve conduit having
appropriate electric (3.8±0.2 mSiemens/cm) and mechanical cues (having young modulus …

Bone marrow mesenchymal stem cells: biological properties and their role in hematopoiesis and hematopoietic stem cell transplantation

C Pontikoglou, F Deschaseaux, L Sensebé… - Stem Cell Reviews and …, 2011 - Springer
Mesenchymal stem cells (MSCs) are multipotent adult stem cells that are present in
practically all tissues as a specialized population of mural cells/pericytes that lie on the …

“Humanized” stem cell culture techniques: the animal serum controversy

C Tekkatte, GP Gunasingh, KM Cherian… - Stem cells …, 2011 - Wiley Online Library
Cellular therapy is reaching a pinnacle with an understanding of the potential of human
mesenchymal stem cells (hMSCs) to regenerate damaged tissue in the body. The limited …

Human mesenchymal stem cells from adipose tissue and amnion influence T-cells depending on stimulation method and presence of other immune cells

B Kronsteiner, S Wolbank, A Peterbauer… - Stem cells and …, 2011 - liebertpub.com
Mesenchymal stem cells (MSCs) are multipotent progenitor cells exerting
immunomodulatory effects on cells of the innate and adaptive immune system. It has been …

Extracellular membrane vesicles from umbilical cord blood-derived MSC protect against ischemic acute kidney injury, a feature that is lost after inflammatory …

L Kilpinen, U Impola, L Sankkila, I Ritamo… - Journal of …, 2013 - Taylor & Francis
Background Mesenchymal stromal cells (MSC) are shown to have a great therapeutic
potential in many immunological disorders. Currently the therapeutic effect of MSCs is …

Mesenchymal stem cells as anti-inflammatories: implications for treatment of Duchenne muscular dystrophy

TE Ichim, DT Alexandrescu, F Solano, F Lara… - Cellular …, 2010 - Elsevier
Duchenne muscular dystrophy (DMD) is a lethal X-linked musculodegenerative condition
consisting of an underlying genetic defect whose manifestation is augmented by …

Cytokine treatment optimises the immunotherapeutic effects of umbilical cord-derived MSC for treatment of inflammatory liver disease

SFH De Witte, AM Merino, M Franquesa, T Strini… - Stem Cell Research & …, 2017 - Springer
Background Mesenchymal stromal cells (MSC) possess immunomodulatory properties and
low immunogenicity, both crucial properties for their development into an effective cellular …

Immune-related antigens, surface molecules and regulatory factors in human-derived mesenchymal stromal cells: the expression and impact of inflammatory priming

M Najar, G Raicevic, HF Kazan, C De Bruyn… - Stem Cell Reviews and …, 2012 - Springer
Based on their ability to regulate immune responses, MSCs are considered to be potential
candidates for managing immune-mediated diseases in the context of immune therapy. AT …