[HTML][HTML] Cerebral small vessel disease: a review focusing on pathophysiology, biomarkers, and machine learning strategies

E Cuadrado-Godia, P Dwivedi, S Sharma… - Journal of …, 2018 - ncbi.nlm.nih.gov
Cerebral small vessel disease (cSVD) has a crucial role in lacunar stroke and brain
hemorrhages and is a leading cause of cognitive decline and functional loss in elderly …

The increasing impact of cerebral amyloid angiopathy: essential new insights for clinical practice

G Banerjee, R Carare, C Cordonnier… - Journal of Neurology …, 2017 - jnnp.bmj.com
Cerebral amyloid angiopathy (CAA) has never been more relevant. The last 5 years have
seen a rapid increase in publications and research in the field, with the development of new …

[HTML][HTML] Glymphatic clearance function in patients with cerebral small vessel disease

W Zhang, Y Zhou, J Wang, X Gong, Z Chen, X Zhang… - Neuroimage, 2021 - Elsevier
Few studies have focused on the connection between glymphatic dysfunction and cerebral
small vessel disease (CSVD), partially due to the lack of non-invasive methods to measure …

Stroke subtype, vascular risk factors, and total MRI brain small-vessel disease burden

J Staals, SDJ Makin, FN Doubal, MS Dennis… - Neurology, 2014 - AAN Enterprises
Objectives: In this cross-sectional study, we tested the construct validity of a “total SVD
score,” which combines individual MRI features of small-vessel disease (SVD) in one …

Perivascular spaces and their associations with risk factors, clinical disorders and neuroimaging features: a systematic review and meta-analysis

F Francis, L Ballerini… - International Journal of …, 2019 - journals.sagepub.com
Background Perivascular spaces, visible on brain magnetic resonance imaging, are thought
to be associated with small vessel disease, neuroinflammation, and to be important for …

Total small vessel disease score and risk of recurrent stroke: validation in 2 large cohorts

KK Lau, L Li, U Schulz, M Simoni, KH Chan, SL Ho… - Neurology, 2017 - AAN Enterprises
Objective: In patients with TIA and ischemic stroke, we validated the total small vessel
disease (SVD) score by determining its prognostic value for recurrent stroke. Methods: Two …

Cerebral small vessel disease: neuroimaging markers and clinical implication

X Chen, J Wang, Y Shan, W Cai, S Liu, M Hu, S Liao… - Journal of …, 2019 - Springer
Cerebral small vessel disease (CSVD) is a broad category of cerebrovascular diseases
which primarily affect the perforating arterioles, capillaries and venules with multiple distinct …

The concept of sporadic cerebral small vessel disease: a road map on key definitions and current concepts

A Charidimou, L Pantoni… - International Journal of …, 2016 - journals.sagepub.com
Sporadic cerebral small vessel disease is considered to be among the most common known
neuropathological processes and has an important role in stroke, cognitive impairment, and …

Total magnetic resonance imaging burden of small vessel disease in cerebral amyloid angiopathy: an imaging-pathologic study of concept validation

A Charidimou, S Martinez-Ramirez, YD Reijmer… - JAMA …, 2016 - jamanetwork.com
Importance Cerebral amyloid angiopathy (CAA) is characteristically associated with
magnetic resonance imaging (MRI) biomarkers of small vessel brain injury, including strictly …

[HTML][HTML] Total MRI load of cerebral small vessel disease and cognitive ability in older people

J Staals, T Booth, Z Morris, ME Bastin, AJ Gow… - Neurobiology of …, 2015 - Elsevier
Cerebral small vessel disease (SVD) may cause cognitive dysfunction. We tested the
association between the combined presence of magnetic resonance imaging (MRI) features …