Impact of Plasmodium falciparum pfhrp2 and pfhrp3 gene deletions on malaria control worldwide: a systematic review and meta-analysis
Background Deletion of pfhrp2 and/or pfhrp3 genes cause false negatives in malaria rapid
diagnostic test (RDT) and threating malaria control strategies. This systematic review aims to …
diagnostic test (RDT) and threating malaria control strategies. This systematic review aims to …
Plasmodium falciparum Histidine-Rich Protein 2 and 3 Gene Deletions and Their Implications in Malaria Control
J Nyataya, J Waitumbi, VA Mobegi, A Noreddin… - Diseases, 2020 - mdpi.com
Malaria remains the biggest threat to public health, especially among pregnant women and
young children in sub-Saharan Africa. Prompt and accurate diagnosis is critical for effective …
young children in sub-Saharan Africa. Prompt and accurate diagnosis is critical for effective …
[HTML][HTML] Plasmodium falciparum pfhrp2 and pfhrp3 gene deletions from persons with symptomatic malaria infection in Ethiopia, Kenya, Madagascar, and Rwanda
E Rogier, JN McCaffery, D Nace, SS Svigel… - Emerging Infectious …, 2022 - ncbi.nlm.nih.gov
Abstract Histidine-rich protein 2 (HRP2)–based rapid diagnostic tests detect Plasmodium
falciparum malaria and are used throughout sub-Saharan Africa. However, deletions in the …
falciparum malaria and are used throughout sub-Saharan Africa. However, deletions in the …
One-step PCR: A novel protocol for determination of pfhrp2 deletion status in Plasmodium falciparum
S Jones, G Subramaniam, MM Plucinski, D Patel… - PLoS …, 2020 - journals.plos.org
Histidine-rich protein 2 (HRP2) detecting rapid diagnostic tests (RDTs) have played an
important role in enabling prompt malaria diagnosis in remote locations. However …
important role in enabling prompt malaria diagnosis in remote locations. However …
Plasmodium falciparum histidine-rich protein 2 diversity in Ghana
Background In the absence of microscopy, Plasmodium falciparum histidine-rich proteins 2
(PfHRP2)-based rapid diagnostic tests (RDTs) are recommended for the diagnosis of …
(PfHRP2)-based rapid diagnostic tests (RDTs) are recommended for the diagnosis of …
Deletion patterns, genetic variability and protein structure of pfhrp2 and pfhrp3: implications for malaria rapid diagnostic test in Amhara region, Ethiopia
I Molina-de la Fuente, M Yimar, L García, V González… - Malaria Journal, 2022 - Springer
Background Although rapid diagnostic tests (RDTs) play a key role in malaria-control
strategies, their efficacy has been threatened by deletion and genetic variability of the genes …
strategies, their efficacy has been threatened by deletion and genetic variability of the genes …
Genetic variation of Plasmodium falciparum histidine-rich protein 2 and 3 in Assosa zone, Ethiopia: its impact on the performance of malaria rapid diagnostic tests
GS Alemayehu, A Messele, K Blackburn, K Lopez, E Lo… - Malaria Journal, 2021 - Springer
Background Rapid diagnostic tests (RDT) are commonly used for the diagnosis of malaria
caused by Plasmodium falciparum. However, false negative results of RDT caused by …
caused by Plasmodium falciparum. However, false negative results of RDT caused by …
Genetic deletions and high diversity of Plasmodium falciparum histidine-rich proteins 2 and 3 genes in parasite populations in Ghana
NO Duah-Quashie, P Opoku-Agyeman… - Frontiers in …, 2022 - frontiersin.org
Rapid diagnostic tests (RDTs) are used to diagnose malaria in Ghana and other malaria
endemic countries. Plasmodium falciparum histidine-rich protein 2 (PFHRP2) based RDTs …
endemic countries. Plasmodium falciparum histidine-rich protein 2 (PFHRP2) based RDTs …
Global polymorphism of Plasmodium falciparum histidine rich proteins 2/3 and impact on malaria rapid diagnostic test detection: a systematic review and meta …
LP Kojom Foko, J Jakhan, G Narang… - Expert Review of …, 2023 - Taylor & Francis
Background This review presents an overview of field findings on sequence variation of
Plasmodium falciparum histidine-rich proteins 2/3 (Pf HRP2/3) for which reference types (1 …
Plasmodium falciparum histidine-rich proteins 2/3 (Pf HRP2/3) for which reference types (1 …
Rapid diagnostic tests failing to detect infections by Plasmodium falciparum encoding pfhrp2 and pfhrp3 genes in a non-endemic setting
G Pasquier, V Azoury, M Sasso, L Laroche… - Malaria Journal, 2020 - Springer
Abstract Background Rapid diagnostic tests (RDTs) detecting the histidine-rich protein 2
(PfHRP2) have a central position for the management of Plasmodium falciparum infections …
(PfHRP2) have a central position for the management of Plasmodium falciparum infections …