Modulating disease-relevant protein-protein interactions (PPIs) using small-molecule
inhibitors is a quite indispensable diagnostic and therapeutic strategy in averting …

Marine natural products have as of now been acknowledged as the most important source of
bioactive substances and drug leads. Marine flora and fauna, such as algae, bacteria …

Class III β-tubulin (βIII-tubulin) is frequently overexpressed in human tumors and is
associated with resistance to microtubule-targeting agents, tumor aggressiveness, and poor …

The 2018 marine pharmacology literature review represents a continuation of the previous
11 reviews of a series initiated in 1998. Preclinical marine pharmacology research during …

The sea is a vast ecosystem that has remained primarily unexploited and untapped,
resulting in numerous organisms. Consequently, marine organisms have piqued the interest …

Microtubules are key components of the eukaryotic cytoskeleton with essential roles in cell
division, intercellular transport, cell morphology, motility, and signal transduction. They are …

In recent decades, the utilization of microwave energy has experienced an extraordinary
surge, leading to the introduction of innovative and revolutionary applications across various …

Ascidians (tunicates) are invertebrate chordates, and prolific producers of a wide variety of
biologically active secondary metabolites from cyclic peptides to aromatic alkaloids. Several …

The natural products of heterobranch molluscs display a huge variability both in structure
and in their bioactivity. Despite the considerable lack of information, it can be observed from …

The discovery of a new drug is a multidisciplinary and very costly task. One of the major
steps is the identification of a lead compound, ie a compound with a certain degree of …