Targeted RNA editing: novel tools to study post-transcriptional regulation
RNA binding proteins (RBPs) regulate nearly all post-transcriptional processes within cells.
To fully understand RBP function, it is essential to identify their in vivo targets. Standard …
To fully understand RBP function, it is essential to identify their in vivo targets. Standard …
GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies
Mutations in the RNA splicing factor gene SF3B1 are common across hematologic and solid
cancers and result in widespread alterations in splicing, yet there is currently no therapeutic …
cancers and result in widespread alterations in splicing, yet there is currently no therapeutic …
[PDF][PDF] The mRNA stability Regulator Khd4 determines infectious hyphae development in Ustilago maydis
S Sankaranarayanan - 2024 - docserv.uni-duesseldorf.de
A key for virulence in many fungal pathogens lies in their capacity for morphological
plasticity, regulated through precise gene expression control. Understanding these infection …
plasticity, regulated through precise gene expression control. Understanding these infection …
Characterisation of mRNA binding proteins as potential therapeutic targets: models and tools
T Kröhler - 2022 - publikationen.sulb.uni-saarland.de
Cancer is one of the most common three causes of premature death worldwide. In past
years, colorectal cancer and primary liver cancer are among the malignancies with the …
years, colorectal cancer and primary liver cancer are among the malignancies with the …