X Dong, W Wu, P Pan, XZ Zhang - Advanced Materials, 2023 - Wiley Online Library
Natural living materials serving as biotherapeutics exhibit great potential for treating various diseases owing to their immunoactivity, tissue targeting, and other biological activities. In this …
Y Zhang, S Wang, Y Yang, S Zhao, J You… - Nature …, 2023 - nature.com
Effective reprogramming of chronic wound healing remains challenging due to the limited drug delivery efficacy hindered by physiological barriers, as well as the inappropriate dosing …
L Yang, D Zhang, W Li, H Lin, C Ding, Q Liu… - Nature …, 2023 - nature.com
The treatment of diabetic wounds faces enormous challenges due to complex wound environments, such as infected biofilms, excessive inflammation, and impaired …
W Xiu, L Wan, K Yang, X Li, L Yuwen, H Dong… - Nature …, 2022 - nature.com
Traditional antibiotic treatment has limited efficacy for the drug-tolerant bacteria present in biofilms because of their unique metabolic conditions in the biofilm infection …
Abstract The International Working Group on the Diabetic Foot (IWGDF) has published evidence‐based guidelines on the prevention and management of diabetic foot disease …
H Chen, Y Cheng, J Tian, P Yang, X Zhang, Y Chen… - Science …, 2020 - science.org
Chronic wounds in diabetes undergo a lifetime risk of developing into diabetic foot ulcers. Oxygen is crucial to wound healing by regulating cell proliferation, migration, and …
Y Kang, L Xu, J Dong, X Yuan, J Ye, Y Fan… - Nature …, 2024 - nature.com
Chronic diabetic wounds are at lifelong risk of developing diabetic foot ulcers owing to severe hypoxia, excessive reactive oxygen species (ROS), a complex inflammatory …
C Lin, J Liu, H Sun - PloS one, 2020 - journals.plos.org
Purpose A considerable number of diabetic foot ulcer (DFU) patients require amputation every year, which worsens their quality of life, aggravates the social burden, and shortens …
H Chen, Y Guo, Z Zhang, W Mao, C Shen, W Xiong… - Nano Letters, 2021 - ACS Publications
Oxidative stress induced by hyperglycemia or chronic inflammation can limit diabetic wound healing, resulting in diabetic foot ulcers. Hydrogen has the potential to act as an antioxidant …